Continuous Monitoring of the Effect of Pentagastrin on Gastric Emptying of Solid Food in Man

Overview

Journal Gut

Specialty Gastroenterology

Date 1976 Apr 1

PMID 773788

Citations 16

Authors

S G HAMILTON

H J Sheiner

M F Quinlan

Affiliations

Soon will be listed here.

Abstract

By continuous monitoring of a solid meal labelled with a radiopharmaceutical it has been possible to determine the effects of drugs on gastric emptying and motility during a single study. Predictably hyoscine delayed, and bethanechol increased, the rate of gastric emptying. Pentagastrin initially produced marked antral activity resulting in a physiological stricture and subsequent delay in the overall rate of gastric emptying. Fundal motility was unaffected though reflux from the antrum occurred.

Citing Articles

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Effects of proton pump inhibitors on gastric emptying: a systematic review.

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Effect of coffee on motor and sensory function of proximal stomach.

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