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Effect of Guanethidine on the Natural History of Post-traumatic Algodystrophy

Overview
Journal Ann Rheum Dis
Specialty Rheumatology
Date 1993 Jun 1
PMID 7686739
Citations 4
Authors
J Field
R M Atkins
Affiliations
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Abstract

Objectives: To determine the effect of intravenous regional guanethidine on post-traumatic algodystrophy.

Methods: Ten of 20 consecutive patients with algodystrophy after Colles' fracture were treated with serial intravenous regional guanethidine blockades and the other 10 were treated with physiotherapy alone. Patients were assessed before and after each block and then monthly over a six month period.

Results: The treated patients had subjective and objective improvements in the assessed features of algodystrophy; treatment resulted in a significant reduction in finger tenderness at five and six months.

Conclusions: Guanethidine blockade induces short term benefits in the symptoms of algodystrophy but improves finger tenderness only in the long term.

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Physiotherapy for pain and disability in adults with complex regional pain syndrome (CRPS) types I and II.

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Treatment of complex regional pain syndrome type I of the hand with a series of intravenous regional sympathetic blocks with guanethidine and lidocaine.

Paraskevas K, Michaloglou A, Briana D, Samara M Clin Rheumatol. 2005; 25(5):687-93.

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[Complex regional pain syndrome I and II. What effects the outcome?].

Gehling M, Tryba M, Niebergall H, Hufschmidt A, Schild M, Geiger K Schmerz. 2003; 17(5):309-16.

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References
1.
Frykman G . Fracture of the distal radius including sequelae--shoulder-hand-finger syndrome, disturbance in the distal radio-ulnar joint and impairment of nerve function. A clinical and experimental study. Acta Orthop Scand. 1967; :Suppl 108:3+. DOI: 10.3109/ort.1967.38.suppl-108.01. View
2.
Woosley R, Nies A . Guanethidine. N Engl J Med. 1976; 295(19):1053-7. DOI: 10.1056/NEJM197611042951906. View
3.
Glynn C, Basedow R, Walsh J . Pain relief following post-ganglionic sympathetic blockade with I.V. guanethidine. Br J Anaesth. 1981; 53(12):1297-302. View
4.
Schutzer S, Gossling H . The treatment of reflex sympathetic dystrophy syndrome. J Bone Joint Surg Am. 1984; 66(4):625-9. View
5.
Huskisson E . Measurement of pain. Lancet. 1974; 2(7889):1127-31. DOI: 10.1016/s0140-6736(74)90884-8. View