Epidemiology of Adult Still's Disease: Estimate of the Incidence by a Retrospective Study in West France

Overview

Journal Ann Rheum Dis

Specialty Rheumatology

Date 1995 Jul 1

PMID 7668903

Citations 103

Authors

G Magadur-Joly

E Billaud

J H Barrier

Y L Pennec

C Masson

P Renou

A Prost

Affiliations

Soon will be listed here.

Abstract

Objectives: To estimate the incidence of adult Still's disease (ASD) and to specify, if possible, associated factors.

Methods: A retrospective study of the populations of the Brittany and Loire regions in west France was made from 1 January 1982 to 31 December 1991. All internal medicine and rheumatology practitioners of these regions were consulted.

Results: Sixty-two (62) cases were reported (93% response). The disease incidence calculated over five years was 0.16 per 100,000 inhabitants in the study population. There was no sex bias (sex ratio 1.06 in ASD v 1.05 in the overall population. The mean age of the study population was 36 years, with two peaks of distribution at 15-25 and 36-45 years. A history of allergy was present in 23% of patients (n = 14). In two patients, it was possible to correlate an environmental allergen to exacerbation of ASD.

Conclusion: The yearly incidence of ASD was estimated to be 0.16 per 100,000 inhabitants. However, it was not possible to incriminate any infectious, toxic, or genetic factors in exacerbation of the disease.

Citing Articles

Does the LDH/Albumin Ratio Bring Novelty? A Comparative Analysis with Inflammatory Indices and Combined Models in Adult-Onset Still's Disease.

Ekin A, Misirci S, Oztop H, Hacimustafaoglu A, Coskun B, Yagiz B Diagnostics (Basel). 2025; 14(24.

PMID: 39767141 PMC: 11674256. DOI: 10.3390/diagnostics14242780.

Overlap of Adult-Onset Still Disease and Kikuchi-Fujimoto Disease: A Case Report and Literature Review.

Donaire-Castanos J, Demelo-Rodriguez P, Ordieres-Ortega L, Pardo-Sanchez S, Galeano-Valle F Cureus. 2024; 16(11):e73283.

PMID: 39650947 PMC: 11625451. DOI: 10.7759/cureus.73283.

Mortality, Length of Stay and Cost of Hospitalization among Patients with Adult-Onset Still's Disease: Results from the National Inpatient Sample 2016-2019.

Mittal S, Schroeder B, Alfaki M Diseases. 2024; 12(7).

PMID: 39057137 PMC: 11276361. DOI: 10.3390/diseases12070166.

Guillain-Barre Syndrome as an Atypical Early Presentation of Adult-Onset Still's Disease: A Case Report.

Al Kaakour J, El-Kojok C, El Mustapha S, Kheirallah J Cureus. 2024; 16(6):e62162.

PMID: 38993449 PMC: 11238750. DOI: 10.7759/cureus.62162.

[The most frequent febrile syndromes and autoinflammatory diseases in adulthood].

Pankow A, Krusche M Z Rheumatol. 2024; 83(5):363-375.

PMID: 38802504 DOI: 10.1007/s00393-024-01522-x.

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