Hepatic Failure in a Case of Multiple Myeloma-associated Amyloidosis (kappa-AL)

Overview

Journal J Gastroenterol

Specialty Gastroenterology

Date 1995 Jun 1

PMID 7647907

Citations 15

Authors

T Yamamoto

N Maeda

H Kawasaki

Affiliations

Soon will be listed here.

Abstract

We report a case of kappa-AL amyloidosis which rapidly developed hepatic failure in a 79-year-old Japanese female who was admitted to our hospital because of abdominal distension and loss of appetite. Laboratory examination revealed a marked deterioration of liver function with cholestasis and monoclonal gammapathy. At the time that the diagnosis of IgG-kappa type multiple myeloma was made, jaundice was advanced, with continuous gastrointestinal bleeding. The patient died of hepatic failure 2 weeks after admission. Needle biopsy of the liver revealed a diffuse, massive deposition of amyloid protein.

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