The Role of MR Imaging in the Diagnosis of Alveolar Soft Part Sarcoma: a Report of 10 Cases

Overview

Journal Skeletal Radiol

Specialties Orthopedics
Radiology

Date 1995 May 1

PMID 7644939

Citations 26

Authors

Y Iwamoto

N Morimoto

H Chuman

N Shinohara

Y Sugioka

Affiliations

Soon will be listed here.

Abstract

Objective: The objective of this study was to analyze the characteristics of alveolar soft part sarcoma using magnetic resonance imaging (MRI).

Design: MRI studies of pathologically proven alveolar soft part sarcomas (ASPS) in ten patients were reviewed and compared with computed tomographic (CT) studies and angiograms.

Patients: Ten patients presented with a soft tissue mass of the extremities, neck, axilla, or buttocks. MR images were obtained in all patients prior to surgical intervention, chemotherapy, or irradiation.

Results And Conclusion: Although most soft tissue sarcomas are isointense relative to muscle or MRI T1-weighted images (T1WI), nine of the ten alveolar ASPS in the present study demonstrated high signal intensity on both T2 and T1WI. Flow voids were observed both at the core and at the margins of the tumors studied. Recognition of these characteristic MRI findings may lead to the early diagnosis of ASPS, especially when the clinical presentation is that of a slow-growing soft tissue mass in a young adult patient.

Citing Articles

Imaging Features of Alveolar Soft Part Sarcoma: Single Institution Experience and Literature Review.

Spinnato P, Papalexis N, Colangeli M, Miceli M, Crombe A, Parmeggiani A Clin Pract. 2023; 13(6):1369-1382.

PMID: 37987424 PMC: 10660714. DOI: 10.3390/clinpract13060123.

The use of the flow-void sign on MRI: highly sensitive sign in detecting bone metastases from renal cell carcinoma.

Murphy J, Rajakulasingam R, Iqbal A, Azzopardi C, Botchu R, Mark Davies A Skeletal Radiol. 2023; 53(5):917-922.

PMID: 37957342 DOI: 10.1007/s00256-023-04512-3.

Management of Metastatic Spine and Hip Alveolar Soft Part Sarcoma: Case Report and Review of Literature.

Shah M, Gadia A, Nene A, Patel P Asian J Neurosurg. 2021; 15(4):1011-1015.

PMID: 33708679 PMC: 7869264. DOI: 10.4103/ajns.AJNS_290_20.

Alveolar soft-part sarcoma: can MRI help discriminating from other soft-tissue tumors? A study of the French sarcoma group.

Crombe A, Brisse H, Ledoux P, Haddag-Miliani L, Bouhamama A, Taieb S Eur Radiol. 2018; 29(6):3170-3182.

PMID: 30560359 DOI: 10.1007/s00330-018-5903-3.

Alveolar soft part sarcoma: the new primary intracranial malignancy : A case report and review of the literature.

Kumar A, Alrohmain B, Taylor W, Bhattathiri P Neurosurg Rev. 2017; 42(1):23-29.

PMID: 28744773 PMC: 6394700. DOI: 10.1007/s10143-017-0874-4.

References

ENTERLINE H . Histopathology of sarcomas. Semin Oncol. 1981; 8(2):133-55. View

SZILAGYI D, Elliott J, DERUSSO F, Smith R . PERIPHERAL CONGENITAL ARTERIOVENOUS FISTULAS. Surgery. 1965; 57:61-81. View

Blumberg M, Chang C . Alveolar soft part sarcoma. South Med J. 1976; 69(3):282-5. DOI: 10.1097/00007611-197603000-00011. View

Lieberman P, FOOTE Jr F, STEWART F, Berg J . Alveolar soft-part sarcoma. JAMA. 1966; 198(10):1047-51. View

Edwards J, HYMAN R, VACIRCA S, Boxer M, Packer S, KAUFMAN I . 0.6 T magnetic resonance imaging of the orbit. AJR Am J Roentgenol. 1985; 144(5):1015-20. DOI: 10.2214/ajr.144.5.1015. View

Rak K, Yakes W, Ray R, Dreisbach J, Parker S, Luethke J . MR imaging of symptomatic peripheral vascular malformations. AJR Am J Roentgenol. 1992; 159(1):107-12. DOI: 10.2214/ajr.159.1.1609682. View

Lorigan J, OKeeffe F, Evans H, Wallace S . The radiologic manifestations of alveolar soft-part sarcoma. AJR Am J Roentgenol. 1989; 153(2):335-9. DOI: 10.2214/ajr.153.2.335. View

ROSENBAUM A, Gabrielsen T, Harris H, Goldberg S . Cerebral manifestations of alveolar soft-part sarcoma. Radiology. 1971; 99(1):109-15. DOI: 10.1148/99.1.109. View

Ekfors T, Kalimo H, Rantakokko V, Latvala M, Parvinen M . Alveolar soft part sarcoma: a report of two cases with some histochemical and ultrastructural observations. Cancer. 1979; 43(5):1672-7. DOI: 10.1002/1097-0142(197905)43:5<1672::aid-cncr2820430517>3.0.co;2-7. View

10.

Daly B, Cheung H, Gaines P, Bradley M, Metreweli C . Imaging of alveolar soft part sarcoma. Clin Radiol. 1992; 46(4):253-6. DOI: 10.1016/s0009-9260(05)80165-5. View

11.

Lieberman P, Brennan M, Kimmel M, Erlandson R, Garin-Chesa P, Flehinger B . Alveolar soft-part sarcoma. A clinico-pathologic study of half a century. Cancer. 1989; 63(1):1-13. DOI: 10.1002/1097-0142(19890101)63:1<1::aid-cncr2820630102>3.0.co;2-e. View

12.

Pettersson H, Gillespy 3rd T, Hamlin D, ENNEKING W, Springfield D, Andrew E . Primary musculoskeletal tumors: examination with MR imaging compared with conventional modalities. Radiology. 1987; 164(1):237-41. DOI: 10.1148/radiology.164.1.3588912. View

13.

PETASNICK J, Turner D, Charters J, Gitelis S, Zacharias C . Soft-tissue masses of the locomotor system: comparison of MR imaging with CT. Radiology. 1986; 160(1):125-33. DOI: 10.1148/radiology.160.1.3715023. View

14.

Berquist T, Ehman R, King B, Hodgman C, Ilstrup D . Value of MR imaging in differentiating benign from malignant soft-tissue masses: study of 95 lesions. AJR Am J Roentgenol. 1990; 155(6):1251-5. DOI: 10.2214/ajr.155.6.2122675. View

15.

CHRISTOPHERSON W, FOOTE Jr F, STEWART F . Alveolar soft-part sarcomas; structurally characteristic tumors of uncertain histogenesis. Cancer. 1952; 5(1):100-11. DOI: 10.1002/1097-0142(195201)5:1<100::aid-cncr2820050112>3.0.co;2-k. View