Worsening to Diabetes in Men with Impaired Glucose Tolerance ("borderline Diabetes")

Overview

Journal Diabetologia

Specialty Endocrinology

Date 1979 Jan 1

PMID 761734

Citations 42

Authors

R J Jarrett

H Keen

J H Fuller

M McCartney

Affiliations

Soon will be listed here.

Abstract

Two hundred and four men with impaired glucose tolerance (borderline diabetes) discovered in a screening examination have been observed for five years and repeated tests of glucose tolerance performed. By pre-determined criteria 27 men 'worsened to diabetes' and this metabolic deterioration was not significantly influenced by treatment with carbohydrate restriction with or without a daily dose of 50 mg phenformin. Of the baseline variables measured prior to treatment allocation only the blood glucose values were significantly predictive of ultimate worsening to diabetes.

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