Molecular Cytogenetics of Human Breast Cancer
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Our studies of human breast cancer using CGH and FISH with precisely mapped probes have revealed a surprising amount of intratumor and intertumor heterogeneity in human breast cancers. However, some regions of abnormal copy number are found frequently. We believe that the regions of frequent abnormality harbor novel cancer genes, and that identification of these is important for diagnosis, prognostication, and the development of new therapies.
Multi-layered cancer chromosomal instability phenotype.
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Classification and feature selection algorithms for multi-class CGH data.
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PMID: 18586749 PMC: 2718623. DOI: 10.1093/bioinformatics/btn145.