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Reconstruction of Metabolic Networks Using Incomplete Information

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Date 1995 Jan 1
PMID 7584429
Citations 5
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Abstract

This paper describes an approach that uses methods for automated sequence analysis (Gaasterland et al. August 1994) and multiple databases accessed through an object+attribute view of the data (Baehr et al. 1992), together with metabolic pathways, reaction equations, and compounds parsed into a logical representation from the Enzyme and Metabolic Pathway Database (Selkov, Yunus, & et.al. 1994), as the sources of data for automatically reconstructing a weighted partial metabolic network for a prokaryotic organism. Additional information can be provided interactively by the expert user to guide reconstruction.

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