Ophthalmoscopy for Congenital Hypertrophy of the Retinal Pigment Epithelium (CHRPE) in Patients with Sporadic Colorectal Carcinoma

Overview

Journal Int J Colorectal Dis

Specialties Gastroenterology
General Surgery

Date 1995 Jan 1

PMID 7561429

Citations 2

Authors

A Hartvigsen

T Myrhoj

S Bulow

K K Borme

J O Sondergaard

I Bernstein

Affiliations

Soon will be listed here.

Abstract

In order to investigate the frequency of congenital hypertrophy of the retinal pigment epithelium (CHRPE) in sporadic colorectal cancer, ophthalmoscopy was carried out in 34 patients with colorectal carcinoma without known familial disposition. CHRPE is one of the most frequent extracolonic manifestations in familial adenomatous polyposis. None of the patients showed any sign of CHRPE. It is concluded that although genetic factors are presumably of importance in the development of sporadic colorectal cancer, CHRPE cannot be used as a marker for future risk of colorectal carcinoma except in polyposis families.

Citing Articles

Congenital hypertrophy of the retinal pigment epithelium (CHRPE) in familial colorectal cancer.

Chen C, Phillips K, Grist S, Bennet G, Craig J, Muecke J Fam Cancer. 2006; 5(4):397-404.

PMID: 16944273 DOI: 10.1007/s10689-006-0011-y.

Extracolonic features of familial adenomatous polyposis in patients with sporadic colorectal cancer.

Dunlop M, Farrington S, Bubb V, Cunningham C, Wright M, Curtis L Br J Cancer. 1996; 74(11):1789-95.

PMID: 8956794 PMC: 2077219. DOI: 10.1038/bjc.1996.631.

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