Regulation of Cellular Calcium Through Signaling Cross-talk Involves an Intricate Interplay Between the Actions of Receptors, G-proteins, and Second Messengers
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Various external stimuli regulate cellular Ca2+ fluxes. Information from these stimuli is transmitted to the cell interior by signal transducing systems that involve interactions between receptors, G-proteins, and enzymes that generate second messengers. The possible mechanisms by which "cross-talk" within and between these second messenger-generating systems provides an intricate molecular avenue for fine modulation of intracellular Ca2+ are reviewed.
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