Cervical Metastasis from the Unknown Primary Tumor

Overview

Journal Eur Arch Otorhinolaryngol

Specialty Otorhinolaryngology

Date 1995 Jan 1

PMID 7546677

Citations 4

Authors

A L Oen

M F de Boer

W C Hop

P Knegt

Affiliations

Soon will be listed here.

Abstract

A retrospective study was performed to examine the results of treatment for cervical lymph node metastases from an unknown primary between 1978 and 1988. We reviewed 66 patients treated with either surgery and/or radiotherapy (n = 41), radiation therapy and chemotherapy (n = 11), combined modality treatment with surgery (n = 8) or with management delayed to proven disease (n = 6). The male-to-female ratio was 5.6 to 1, and the median age was 64 years (range, 15-89 years). Intercurrent death-corrected 5-year survival was 50%. The most important prognostic factors were M category and involvement of supraclavicular nodes. Primary tumor was eventually discovered in 12 patients during follow-up, 6 of whom received treatment with curative intent. The most common site of primary tumor was found to be the lung (n = 5).

Citing Articles

Metastatic Squamous Cell Carcinoma to the Cervical Lymph Nodes From an Unknown Primary Cancer: Management in the HPV Era.

Civantos F, Vermorken J, Shah J, Rinaldo A, Suarez C, Kowalski L Front Oncol. 2020; 10:593164.

PMID: 33244460 PMC: 7685177. DOI: 10.3389/fonc.2020.593164.

The role of transoral robotic surgery, transoral laser microsurgery, and lingual tonsillectomy in the identification of head and neck squamous cell carcinoma of unknown primary origin: a systematic review.

Fu T, Foreman A, Goldstein D, de Almeida J J Otolaryngol Head Neck Surg. 2016; 45(1):28.

PMID: 27142355 PMC: 4855481. DOI: 10.1186/s40463-016-0142-6.

Diagnosis and management of neck metastases from an unknown primary.

Calabrese L, Jereczek-Fossa B, Jassem J, Rocca A, Bruschini R, Orecchia R Acta Otorhinolaryngol Ital. 2005; 25(1):2-12.

PMID: 16080309 PMC: 2639847.

Diagnosis and management of carcinoma of unknown primary in the head and neck.

Issing W, Taleban B, Tauber S Eur Arch Otorhinolaryngol. 2003; 260(8):436-43.

PMID: 12684829 DOI: 10.1007/s00405-003-0585-z.

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