An Autosomal Genetic Linkage Map of the Sheep Genome

Overview

Journal Genetics

Publisher Oxford University Press

Specialty Genetics

Date 1995 Jun 1

PMID 7498748

Citations 61

Authors

A M Crawford

K G Dodds

A J Ede

C A Pierson

G W Montgomery

H G Garmonsway

A E Beattie

K Davies

J F Maddox

S W Kappes

Affiliations

Soon will be listed here.

Abstract

We report the first extensive ovine genetic linkage map covering 2070 cM of the sheep genome. The map was generated from the linkage analysis of 246 polymorphic markers, in nine three-generation full-sib pedigrees, which make up the AgResearch International Mapping Flock. We have exploited many markers from cattle so that valuable comparisons between these two ruminant linkage maps can be made. The markers, used in the segregation analyses, comprised 86 anonymous microsatellite markers derived from the sheep genome, 126 anonymous microsatellites from cattle, one from deer, and 33 polymorphic markers of various types associated with known genes. The maximum number of informative meioses within the mapping flock was 222. The average number of informative meioses per marker was 140 (range 18-209). Linkage groups have been assigned to all 26 sheep autosomes.

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