Thermostability and Aliphatic Index of Globular Proteins

Overview

Journal J Biochem

Publisher Oxford University Press

Specialty Biochemistry

Date 1980 Dec 1

PMID 7462208

Citations 420

Authors

A Ikai

Affiliations

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Abstract

A statistical analysis shows that the aliphatic index, which is defined as the relative volume of a protein occupied by aliphatic side chains (alanine, valine, isoleucine, and leucine), of proteins of thermophilic bacteria is significantly higher than that of ordinary proteins. The index may be regarded as a positive factor for the increase of thermostability of globular proteins.

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