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Serological Response to Campylobacter Jejuni/coli Infection

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Journal J Clin Pathol
Specialty Pathology
Date 1980 Aug 1
PMID 7430389
Citations 13
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Abstract

The antibody response to Campylobacter jejuni/coli infection was investigated in 59 patients involved in two outbreaks of milk-borne infection and in sporadic infections in the community. Agglutinins and complement-fixing (CF) antibodies were detected in nearly all these patients. Agglutinins were present in 25% of normal sera at low titres (not greater than 1/160) but CF antibody titres of 1/4 or 1/8 were present in only 2.0%. The agglutination reactions in convalescent sera were best developed with the homologous or an antigenically similar strain whereas the CF test, with sonicated organisms as antigen, was less strain-specific and was more suitable as a routine test. Antibody was present seven to 10 days after the onset of symptoms.

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