Base Composition of Rubella Virus RNA. Brief Report

Overview

Journal Arch Virol

Specialty Microbiology

Date 1980 Jan 1

PMID 7425851

Citations 4

Authors

S Katow

T Matsuno

Affiliations

Soon will be listed here.

Abstract

The base composition of 32P-labelled RNA of rubella virus was shown to be; Gp:31.1, Ap:21.9, Cp:34.3 and Up:12.8 per 100 nucleotides. The result demonstrates that the virus is distinct from other members of family Togaviridae in that it possesses RNA with relatively high contents of Gp and Cp, and low content of Up. Viral RNA adsorbed to oligo (dT)-cellulose column was shown to be infectious, whereas no infectivity of RNA appearing in the void volume was found. This may indicate that viral RNA needs to carry a minimal length of poly(A) to be infectious.

Citing Articles

Effect of the infection of rubella virus on BHK 21/13 s cells: study of a glycolipid.

Bardeletti G, Voiland A Arch Virol. 1981; 68(3-4):285-9.

PMID: 7271460 DOI: 10.1007/BF01314583.

Changes in antibody avidity after virus infections: detection by an immunosorbent assay in which a mild protein-denaturing agent is employed.

Inouye S, Hasegawa A, Matsuno S, Katow S J Clin Microbiol. 1984; 20(3):525-9.

PMID: 6092430 PMC: 271364. DOI: 10.1128/jcm.20.3.525-529.1984.

Antibody response to individual rubella virus proteins in congenital and other rubella virus infections.

Katow S, Sugiura A J Clin Microbiol. 1985; 21(3):449-51.

PMID: 3980696 PMC: 271684. DOI: 10.1128/jcm.21.3.449-451.1985.

Monoclonal antibodies directed to E1 glycoprotein of rubella virus.

Umino Y, Sato T, Katow S, Matsuno T, Sugiura A Arch Virol. 1985; 83(1-2):33-42.

PMID: 2578781 DOI: 10.1007/BF01310962.

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