Cellular Events in Denervated Limb Stumps of Ambystoma Larvae During Re-innervation and Subsequent Regeneration

Overview

Journal Experientia

Specialty Science

Date 1980 May 15

PMID 7379971

Citations 3

Authors

N S Petrosky

R A Tassava

C L Olsen

Affiliations

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Abstract

Amputated, denervated Ambystoma forelimbs undergo cellular dedifferentiation and slight resorption through 12 days post-amputation. Subsequently, as limb stumps become re-innervated, there occur mitosis, blastema formation, and regeneration. The initial increase in the mitotic index in once-denervated limb stumps is closely correlated with the presence of ingrowing nerve fibres.

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References

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