Drug Innovation--what's Slowing It Down?
Authors
Affiliations
Predictive validity in drug discovery: what it is, why it matters and how to improve it.
Scannell J, Bosley J, Hickman J, Dawson G, Truebel H, Ferreira G Nat Rev Drug Discov. 2022; 21(12):915-931.
PMID: 36195754 DOI: 10.1038/s41573-022-00552-x.
Diagnosing the decline in pharmaceutical R&D efficiency.
Scannell J, Blanckley A, Boldon H, Warrington B Nat Rev Drug Discov. 2012; 11(3):191-200.
PMID: 22378269 DOI: 10.1038/nrd3681.
The regulatory control of non-steroidal anti-inflammatory agents.
Dukes M, Lunde I Eur J Clin Pharmacol. 1981; 19(1):3-10.
PMID: 7461020 DOI: 10.1007/BF00558371.
The drug industry: the goose that lays the golden drugs.
Smith T Br Med J. 1980; 281(6250):1255-7.
PMID: 7427658 PMC: 1714676. DOI: 10.1136/bmj.281.6250.1255.
A survey of products licensed in the United Kingdom from 1971-1981.
Griffin J, Diggle G Br J Clin Pharmacol. 1981; 12(4):453-63.
PMID: 7028062 PMC: 1401882. DOI: 10.1111/j.1365-2125.1981.tb01251.x.