Article: The mild form of Hirschsprung's disease (short segment): fourteen-years experience in diagnosis and treatment

From 1966 through 1980, 39 children were treated with anorectal myectomy for the mild form of Hirschsprung's disease. The mild form of Hirschsprung's disease is differentiated from the severe one mainly on clinical grounds. Of the entire group, only four patients needed a Duhamel procedure, one to three years after myectomy. One patient still uses occasional enema (11 years after operation). The remaining 34 patients are symptom-free (1--14 years after operation). Anorectal myectomy is the treatment of choice in the management of the mild form of Hirschsprung's disease.

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References

1.

Shandling B, DESJARDINS J . Anal myomectomy for constipation. J Pediatr Surg. 1969; 4(1):115-8. DOI: 10.1016/0022-3468(69)90191-2. View

2.

THOMAS Jr C . Posterior sphincterotomy in Hirschsprung's disease. Surg Gynecol Obstet. 1967; 124(2):365-6. View

3.

Davidson M, Bauer C . Studies of distal colonic motility in children. IV. Achalasia of the distal rectal segment despite presence of ganglia in the myenteric plexuses of this area. Pediatrics. 1958; 21(5):746-61. View

4.

THOMAS Jr C, BREAM C, DeConnick P . Posterior sphincterotomy and rectal myotomy in the management of Hirschsprung's disease. Ann Surg. 1970; 171(5):796-810. PMC: 1396795. DOI: 10.1097/00000658-197005000-00020. View

5.

BAR-MAOR J, Nissan S . A simple recording system for the diagnosis of Hirschsprung's disease and idiopathic megacolon. Surg Gynecol Obstet. 1973; 136(5):795-6. View

6.

Vinograd I, Lernau O, Rosenmann E, Nissan S . [Combined method for the diagnosis of Hirschsprung's disease]. Harefuah. 1978; 95(3-4):103-4. View

7.

Nissan S, BAR-MAOR J, Levy E . Anorectal myomectomy in the treatment of short segment Hirschsprung's disease. Ann Surg. 1969; 170(6):969-77. PMC: 1387726. DOI: 10.1097/00000658-196912000-00017. View

8.

Lynn H . Rectal myectomy for aganglionic megacolon. Mayo Clin Proc. 1966; 41(5):289-95. View

9.

SOPER R, MILLER F . Congenital aganglionic megacolon (Hirschsprung's disease). Diagnosis, management, and complications. Arch Surg. 1968; 96(4):554-62. DOI: 10.1001/archsurg.1968.01330220070013. View

10.

Alexander J, Aston S . A technique for posterior myectomy and internal sphincterotomy in short-segment Hirschsprung's disease. J Pediatr Surg. 1974; 9(2):169-70. DOI: 10.1016/s0022-3468(74)80115-6. View

11.

Nixon H . HIRSCHSPRUNG'S DISEASE. Arch Dis Child. 1964; 39:109-15. PMC: 2019120. DOI: 10.1136/adc.39.204.109. View

12.

Scobie W, Mackinlay G . Anorectal myectomy in treatment of ultrashort segment Hirschsprung's disease. Report of 26 cases. Arch Dis Child. 1977; 52(9):713-5. PMC: 1544747. DOI: 10.1136/adc.52.9.713. View

13.

Lynn H, Van Heerden J . Rectal myectomy in Hirschsprung disease: a decade of experience. Arch Surg. 1975; 110(8):991-4. DOI: 10.1001/archsurg.1975.01360140135026. View

The Mild Form of Hirschsprung's Disease (short Segment): Fourteen-years Experience in Diagnosis and Treatment