Soluble Immune Complexes in Patients with Diabetes Mellitus: Detection and Pathological Significance

Overview

Journal Diabetologia

Specialty Endocrinology

Date 1981 Sep 1

PMID 7297792

Citations 13

Authors

G Virella

H Wohltmann

J Sagel

M F Lopes-Virella

M Kilpatrick

C Phillips

J Colwell

Affiliations

Soon will be listed here.

Citing Articles

α1Proteinase inhibitor regulates CD4+ lymphocyte levels and is rate limiting in HIV-1 disease.

Bristow C, Babayeva M, LaBrunda M, Mullen M, Winston R PLoS One. 2012; 7(2):e31383.

PMID: 22363634 PMC: 3281957. DOI: 10.1371/journal.pone.0031383.

High levels of oxidized LDL in circulating immune complexes are associated with increased odds of developing abnormal albuminuria in Type 1 diabetes.

Lopes-Virella M, Carter R, Baker N, Lachin J, Virella G Nephrol Dial Transplant. 2011; 27(4):1416-23.

PMID: 21856760 PMC: 3471550. DOI: 10.1093/ndt/gfr454.

Distribution of IgM and IgG antibodies to oxidized LDL in immune complexes isolated from patients with type 1 diabetes and its relationship with nephropathy.

Virella G, Carter R, Saad A, Crosswell E, Game B, Lopes-Virella M Clin Immunol. 2008; 127(3):394-400.

PMID: 18533284 PMC: 2601558. DOI: 10.1016/j.clim.2008.02.005.

Lipoprotein autoantibodies: measurement and significance.

Virella G, Lopes-Virella M Clin Diagn Lab Immunol. 2003; 10(4):499-505.

PMID: 12853376 PMC: 164259. DOI: 10.1128/cdli.10.4.499-505.2003.

Self antigen prognostic for human immunodeficiency virus disease progression.

Bristow C, Patel H, Arnold R Clin Diagn Lab Immunol. 2001; 8(5):937-42.

PMID: 11527807 PMC: 96175. DOI: 10.1128/CDLI.8.5.937-942.2001.

References

Zubler R, LANGE G, Lambert P, MIESCHER P . Detection of immune complexes in unheated sera by modified 125I-Clq binding test. Effect of heating on the binding of Clq by immune complexes and application of the test to systemic lupus erythematosus. J Immunol. 1976; 116(1):232-5. View

Tung K, Kim B, Bjorvatn B, Kronvall G, McLaren L, Williams Jr R . Discrepancy between Clq deviation and Raji cell tests in detection of circulating immune complexes in patients with leprosy. J Infect Dis. 1977; 136(2):216-21. DOI: 10.1093/infdis/136.2.216. View

Irvine W, Di Mario U, Guy K, Iavicoli M, Pozzilli P, Lumbroso B . Immune complexes and diabetic microangiopathy. J Clin Lab Immunol. 1978; 1(3):187-91. View

Virella G, Russell D, Laimins M, Colwell J . Simplified method for detecting anti-insulin antibodies and insulin-anti-insulin immune complexes. Clin Chem. 1980; 26(9):1357-9. View

Herbert V, Lau K, Gottlieb C, Bleicher S . Coated charcoal immunoassay of insulin. J Clin Endocrinol Metab. 1965; 25(10):1375-84. DOI: 10.1210/jcem-25-10-1375. View

Hardin J, Walker L, Steere A, Trumble T, Tung K, Williams Jr R . Circulating immune complexes in Lyme arthritis. Detection by the 125I-C1q binding, C1q solid phase, and Raji cell assays. J Clin Invest. 1979; 63(3):468-77. PMC: 371975. DOI: 10.1172/JCI109324. View

Milgrom F, Kano K . Comparison of various procedures for the detection of antigen-antibody complexes. Int Arch Allergy Appl Immunol. 1978; 56(3):224-31. DOI: 10.1159/000232025. View

Lopes-Virella M, Virella G, Rosebrock G, Sagel J, Gonzalez J, Colwell J . Early diagnosis of renal malfunction in diabetics. Abnormal proteinuria revealed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Diabetologia. 1979; 16(3):165-71. DOI: 10.1007/BF01219793. View

Irvine W, Di Mario U, Feek C, Gray R, EDMOND B, Duncan L . Soluble immune complexes in the sera of newly diagnosed insulin-dependent diabetics and in treated diabetics. Clin Exp Immunol. 1977; 30(1):16-21. PMC: 1541180. View

10.

Jayarao K, Faulk W, KARAM J, GRODSKY G, FORSHAM P . Measurement of immune complexes in insulin-treated diabetics. J Immunol Methods. 1973; 3(4):337-45. DOI: 10.1016/0022-1759(73)90035-5. View

11.

Pires M, da Cunha A, Virella G, Simoes J . Analytical characterization of urinary proteins by sodium dodecyl sulphate-polyacrylamide gel electrophoresis in renal disease. Clinical and histopathological correlations. Nephron. 1975; 14(5):361-72. DOI: 10.1159/000180466. View

12.

Gupta R, MCDUFFIE F, Huston K, Tappeiner G, Meurer M, Jordon R . Comparison of three immunoassays for immune complexes in rheumatoid arthritis. Arthritis Rheum. 1979; 22(5):433-9. DOI: 10.1002/art.1780220501. View

13.

Faulk W, KARAM J, Fudenberg H . Human anti-insulin antibodies. J Immunol. 1971; 106(4):1112-6. View

14.

Kilpatrick J, Virella G . Isolation and characterization of soluble insulin-anti-insulin immune complexes formed in vitro and in vivo in sera from patients with diabetes mellitus. Clin Exp Immunol. 1980; 40(3):445-52. PMC: 1538931. View

15.

Halla J, Volanakis J, Schrohenloher R . Circulating immune complexes in mixed connective tissue disease. Arthritis Rheum. 1979; 22(5):484-9. DOI: 10.1002/art.1780220507. View

16.

Tung K, Woodroffe A, Ahlin T, Williams Jr R, Wilson C . Application of the solid phase C1q and Raji cell radioimmune assays for the detection of circulating immune complexes in glomerulonephritis. J Clin Invest. 1978; 62(1):61-72. PMC: 371737. DOI: 10.1172/JCI109115. View

17.

Deaton C, MAXWELL K, Smith R, CREVELING R . Use of laser nephelometry in the measurement of serum proteins. Clin Chem. 1976; 22(9):1465-71. View

18.

Mustaffa B, Daggett P, Nabarro J . Insulin binding capacity in patients changed from conventional to highly purified insulins. An indicator of likely response. Diabetologia. 1977; 13(4):311-5. DOI: 10.1007/BF01223271. View

19.

Delespesse G, Gausset P, Sarfati M, Debisschop M, Van Haelst L . Circulating immune complexes in old people and in diabetics: correlation with autoantibodies. Clin Exp Immunol. 1980; 40(1):96-102. PMC: 1536959. View

20.

Virella G, Hipp W, John Jr J, Kahaleh B, Ford M, Fudenberg H . Nephelometric detection of soluble immune complexes: methodology and clinical applications. Int Arch Allergy Appl Immunol. 1979; 58(4):402-10. DOI: 10.1159/000232219. View