Changes in the Concentration of Vasoactive Intestinal Peptide in Intestinal Lymph in Response to Vagal Stimulation in the Calf

Overview

Journal Experientia

Specialty Science

Date 1978 Sep 15

PMID 720519

Citations 7

Authors

A V Edwards

P M Birchman

S J Mitchell

S R Bloom

Affiliations

Soon will be listed here.

Abstract

Stimulation of both vagi caused a significant rise in arterial plasma vasoactive intestinal peptide (VIP) concentration in 3--5-week-old calves with cut splanchnic nerves. This was associated with a pronounced rise in the VIP concentration of intestinal lymph showing that vagal stimulation causes release of VIP from splanchnic viscera.

Citing Articles

Immunohistochemical localization and vascular effects of vasoactive intestinal polypeptide in skeletal muscle of the cat.

Jarhult J, Hellstrand P, Sundler F Cell Tissue Res. 1980; 207(1):55-64.

PMID: 7388912 DOI: 10.1007/BF00239329.

Mechanism of action of vasoactive intestinal polypeptide on myometrial smooth muscle of rabbit and guinea-pig.

Bolton T, Lang R, Ottesen B J Physiol. 1981; 318:41-55.

PMID: 7320897 PMC: 1245476. DOI: 10.1113/jphysiol.1981.sp013849.

The pharmacokinetics of VIP in dog and pig.

Mitchell S, Modlin I, DSa Barros A, Bloom S Experientia. 1982; 38(9):1091-3.

PMID: 7128757 DOI: 10.1007/BF01955385.

Pancreatic endocrine responses to stimulation of the peripheral ends of the vagus nerves in conscious calves.

Bloom S, Edwards A J Physiol. 1981; 315:31-41.

PMID: 7031230 PMC: 1249365. DOI: 10.1113/jphysiol.1981.sp013730.

Effects of autonomic stimulation on the release of vasoactive intestinal peptide from the gastrointestinal tract in the calf.

Bloom S, Edwards A J Physiol. 1980; 299:437-52.

PMID: 6991667 PMC: 1279235. DOI: 10.1113/jphysiol.1980.sp013135.

References

Sundler F, Alumets J, Hakanson R, Ingemansson S, Fahrenkrug J, Schaffalitzky de Muckadell O . VIP innervation of the gallbladder. Gastroenterology. 1977; 72(6):1375-7. View

Schaffalitzky de Muckadell O, Fahrenkrug J, Holst J . Release of vasoactive intestinal polypeptide (VIP) by electric stimulation of the vagal nerves. Gastroenterology. 1977; 72(2):373-5. View

Bryant M, Polak M, Modlin I, Bloom S, Albuquerque R, Pearse A . Possible dual role for vasoactive intestinal peptide as gastrointestinal hormone and neurotransmitter substance. Lancet. 1976; 1(7967):991-3. DOI: 10.1016/s0140-6736(76)91863-8. View

Bloom S, Polak J, Pearse A . Vasoactive intestinal peptide and watery-diarrhoea syndrome. Lancet. 1973; 2(7819):14-6. DOI: 10.1016/s0140-6736(73)91947-8. View

Larsson L, Fahrenkrug J, Schaffalitzky de Muckadell O, Sundler F, Hakanson R, Rehfeld J . Localization of vasoactive intestinal polypeptide (VIP) to central and peripheral neurons. Proc Natl Acad Sci U S A. 1976; 73(9):3197-200. PMC: 430979. DOI: 10.1073/pnas.73.9.3197. View