Alpha 2.0
Login Register
» Articles » PMID: 720295

Levels of Lead and Other Metals in Human Blood: Suggestive Relationships, Determining Factors

Overview
Journal Environ Health Perspect
Date 1978 Aug 1
PMID 720295
Citations 14
Authors
R L ZIELHUIS
P del Castilho
R F Herber
A A Wibowo
Affiliations
Soon will be listed here.
Abstract

Epidemiological studies on metal levels in blood were carried out. Evidence suggested the existence of a different trend in serum-iron levels in relation to blood lead levels in nonoccupationally exposed males (negative trend) and females (positive trend). There was a positive relation between blood lead levels and blood manganese levels in children and occupationally exposed male workers. Blood metal levels increased with age in young children. There was evidence for an influence of socioeconomic class on blood lead levels in children. A direct and an indirect effect of smoking was found on blood lead levels and on the activity of delta-aminolevulinic acid dehydratase activity in erythrocytes in adult nonoccupationally exposed females.

Citing Articles

Developmental manganese, lead, and barren cage exposure have adverse long-term neurocognitive, behavioral and monoamine effects in Sprague-Dawley rats.

Sprowles J, Amos-Kroohs R, Braun A, Sugimoto C, Vorhees C, Williams M Neurotoxicol Teratol. 2018; 67:50-64.

PMID: 29631003 PMC: 5970996. DOI: 10.1016/j.ntt.2018.04.001.

Longitudinal T1 relaxation rate (R1) captures changes in short-term Mn exposure in welders.

Lewis M, Flynn M, Lee E, Van Buren S, Van Buren E, Du G Neurotoxicology. 2016; 57:39-44.

PMID: 27567731 PMC: 5123898. DOI: 10.1016/j.neuro.2016.08.012.

Effect of Hfe Deficiency on Memory Capacity and Motor Coordination after Manganese Exposure by Drinking Water in Mice.

Alsulimani H, Ye Q, Kim J Toxicol Res. 2016; 31(4):347-54.

PMID: 26877837 PMC: 4751444. DOI: 10.5487/TR.2015.31.4.347.

DNA methylation changes in the placenta are associated with fetal manganese exposure.

Maccani J, Koestler D, Houseman E, Armstrong D, Marsit C, Kelsey K Reprod Toxicol. 2015; 57:43-9.

PMID: 25982381 PMC: 4550511. DOI: 10.1016/j.reprotox.2015.05.002.

Loss of hfe function reverses impaired recognition memory caused by olfactory manganese exposure in mice.

Ye Q, Kim J Toxicol Res. 2015; 31(1):17-23.

PMID: 25874029 PMC: 4395651. DOI: 10.5487/TR.2015.31.1.017.

References
1.
McDonald R, Marshall S . THE VALUE OF IRON THERAPY IN PICA. Pediatrics. 1964; 34:558-62. View
2.
GUTELIUS M, MILLICAN F, LAYMAN E, COHEN G, DUBLIN C . Nutritional studies of children with pica. I Controlled study evaluating nutritional status. Pediatrics. 1962; 29:1012-23. View
3.
del Castilho P, Herber R . The rapid determination of cadmium, lead, copper and zinc in whole blood by atomic absorption spectrometry with electrothermal atomization. Improvements in precision with a peak-shape monitoring device. Anal Chim Acta. 1977; 94(2):269-74. DOI: 10.1016/s0003-2670(01)84526-8. View
4.
Salle H, ZIELHUIS R . Influence of smoking on aminolevulinic acid dehydratase activity, haematocrite and lead in blood in adult urban women. Int Arch Occup Environ Health. 1977; 40(2):111-5. DOI: 10.1007/BF00575155. View
5.
ADEBONOJO F . Subclinical lead burden: relation to hemoglobin and hematocrit values. Pa Med. 1975; 78(3):63-5. View