Adamantinoma of Long Bones: Clinical, Pathological and Ultrastructural Features

Overview

Journal J Clin Pathol

Specialty Pathology

Date 1982 Jul 1

PMID 7201477

Citations 7

Authors

A S Pieterse

P S Smith

J McClure

Affiliations

Soon will be listed here.

Abstract

The clinical, pathological and ultrastructural features of two cases of tibial adamantinoma are described. Both lesions showed identical features with a mixed histological picture exhibiting baseloid, tubular and squamous differentiation and a prominent stromal (mesenchymal) component. By light microscopy there appeared to be an intimate relation between the epithelial and mesenchymal components. By electromicroscopy the cellular constituents of these components could be readily distinguished. In the former the cells contained tonofilaments and desmosomes which were associated with basement membrane material. In the latter (mesenchymal component) none of these features was notes, instead the cells appeared similar to fibroblasts and occasional myofibroblasts.

Citing Articles

Femoral Adamantinoma: A Rare Lesion in an Elderly Patient in a Rare Location.

Aydin B, Khan Z, Er T, Ugras S Balkan Med J. 2017; 34(2):185-186.

PMID: 28418350 PMC: 5394304. DOI: 10.4274/balkanmedj.2016.1534.

The Complimentary Role of Methoxy-Isobutyl-Isonitrile and Hand-Held Gamma Probe in Adamantinoma.

Maharaj M, Korowlay N, Ellmann P World J Nucl Med. 2016; 15(1):50-2.

PMID: 26912979 PMC: 4729015. DOI: 10.4103/1450-1147.167600.

First Confirmed Metastatic Adamantinoma of the Spine: Case Report and Literature Review.

Morales Ciancio R, Gasbarrini A, Boriani S, Gambarotti M Global Spine J. 2015; 5(4):e7-e12.

PMID: 26225294 PMC: 4516730. DOI: 10.1055/s-0034-1394362.

Adamantinoma of the tibia: a case report.

Ramesh R, Burrah R, Thambuchetty N, ShivaKumar K, Ananthamurthy A, Manjunath S Indian J Surg Oncol. 2013; 3(3):239-41.

PMID: 23997514 PMC: 3444592. DOI: 10.1007/s13193-012-0168-9.

Adamantinoma of long bones: a long-term follow-up study of 11 cases.

Szendroi M, Antal I, Arato G Pathol Oncol Res. 2008; 15(2):209-16.

PMID: 19048403 DOI: 10.1007/s12253-008-9125-x.

References

McNutt N . Ultrastructural comparison of the interface between epithelium and stroma in basal cell carcinoma and control human skin. Lab Invest. 1976; 35(2):132-42. View

Malech H, Lentz T . Microfilaments in epidermal cancer cells. J Cell Biol. 1974; 60(2):473-82. PMC: 2109157. DOI: 10.1083/jcb.60.2.473. View

DIEPEVEEN W, HJORT G, POCK-STEEN O . Adamantinoma of the capitate bone. Acta Radiol (Stockh). 1960; 53:377-84. DOI: 10.3109/00016926009171687. View

Huvos A, Marcove R . Adamantinoma of long bones. A clinicopathological study of fourteen cases with vascular origin suggested. J Bone Joint Surg Am. 1975; 57(2):148-54. View

Rosen R, SCHWINN C . Adamantinoma of limb bone. Malignant angioblastoma. Am J Roentgenol Radium Ther Nucl Med. 1966; 97(3):727-32. DOI: 10.2214/ajr.97.3.727. View

Lasda N, Hughes Jr E . Adamantinoma of the ischium. Case report. J Bone Joint Surg Am. 1979; 61(4):599-600. View

van Haelst U, de Haas van Dorsser A . A perplexing malignant bone tumor. Highly malignant so-called adamantinoma or non-typical Ewing's sarcoma. Virchows Arch A Pathol Anat Histol. 1975; 365(1):63-74. DOI: 10.1007/BF00439285. View

Braidwood A, McDougall A . Adamantinoma of the tibia. Report of two cases. J Bone Joint Surg Br. 1974; 56-B(4):735-8. DOI: 10.1302/0301-620X.56B4.735. View

Gabbiani G, Trenchev P, HOLBOROW E . Increase of contractile proteins in human cancer cells. Lancet. 1975; 2(7939):796-7. DOI: 10.1016/s0140-6736(75)80008-0. View

10.

NAJI A, Murphy J, STASNEY R, NEVILLE W, CHRENKA P . SO-CALLED ADAMANTINOMA OF LONG BONES. J Bone Joint Surg Am. 1964; 46:151-8. View

11.

Yoneyama T, WINTER W, Milsow L . Tibial adamantinoma: its histogenesis from ultrastructural studies. Cancer. 1977; 40(3):1138-42. DOI: 10.1002/1097-0142(197709)40:3<1138::aid-cncr2820400324>3.0.co;2-u. View

12.

BAKER P, DOCKERTY M, COVENTRY M . Adamantinoma (so-called) of the long bones; review of the literature and report of three new cases. J Bone Joint Surg Am. 1954; 36-A(4):704-20. View

13.

Lederer H, Sinclair A . Malignant synovioma simulating "adamantinoma of the tibia". J Pathol Bacteriol. 1954; 67(1):163-8. DOI: 10.1002/path.1700670120. View

14.

Rosai J . Adamantinoma of the tibia. Electron microscopic evidence of its epithelial origin. Am J Clin Pathol. 1969; 51(6):786-92. DOI: 10.1093/ajcp/51.6.786. View

15.

Cohen D, Dahlin D, PUGH D . Fibrous dysplasia associated with adamantinoma of the long bones. Cancer. 1962; 15:515-21. DOI: 10.1002/1097-0142(196205/06)15:3<515::aid-cncr2820150311>3.0.co;2-2. View

16.

Unni K, Dahlin D, Beabout J, IVINS J . Adamantinomas of long bones. Cancer. 1974; 34(5):1796-805. DOI: 10.1002/1097-0142(197411)34:5<1796::aid-cncr2820340530>3.0.co;2-z. View

17.

Mangalik V, MEHROTRA R . Adamantinoma of the tibia; report of a case. Br J Surg. 1952; 39(157):429-32. DOI: 10.1002/bjs.18003915706. View

18.

DAMERON Jr T . Adamantinoma of the appendicular skeleton. Johns Hopkins Med J. 1979; 145(3):107-11. View

19.

Donner R, Dikland R . Adamantinoma of the tibia. A long-standing case with unusual histological features. J Bone Joint Surg Br. 1966; 48(1):138-44. View

20.

Toh B, Muller H . Smooth muscle-associated antigen in experimental cutaneous squamous cell carcinoma, keratoacanthoma, and papilloma. Cancer Res. 1975; 35(12):3741-5. View