On the Origin of Z-band Material and Myofilaments in Myoblasts from the Human Atrial Wall

Overview

Journal Cell Tissue Res

Specialties Anatomy & Histology
Cell Biology

Date 1980 Jan 1

PMID 7190069

Citations 2

Authors

T Saetersdal

H Engedal

R LIE

R Myklebust

Affiliations

Soon will be listed here.

Abstract

The origin of cardiac myofibrils in cells from the atrial wall in human embryos was studied, Z-band substance appears throughout the cytoplasm as irregular electron dense patches in a network of thin filaments. The thin and thick filaments are synthesized as separate units in the sarcoplasm and are later aggregated into myofibrils. Complexes of Z substance and thin filaments occur numerously at different stages of myofibrillar organisation. Thick filaments are formed in close proximity to free ribosomes and are later incorporated in an hexagonal pattern into the Z-band/thin filament complex.

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