Single-point Prediction Methods: a Critical Review

Overview

Journal Drug Intell Clin Pharm

Specialties Pharmacology
Pharmacy

Date 1982 Nov 1

PMID 7173047

Citations 4

Authors

J R Koup

Affiliations

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Abstract

This article presents a critical review of a proposed method of dose prediction. Previously published experiences with this method are reviewed. New applications with drugs that have short elimination half-lives and drugs that demonstrate nonlinearity of clearance are discussed. Potential sources of error are demonstrated, using computer simulations.

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