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Binding of Heme by Glutathione S-transferase: a Possible Role of the Erythrocyte Enzyme

Overview
Journal Blood
Publisher Elsevier
Specialty Hematology
Date 1982 Nov 1
PMID 7126873
Citations 25
Authors
Affiliations
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Abstract

Human erythrocyte glutathione S-transferase activity is inhibited, probably competitively, by hemin with a Ki of 10(-7) M. It is postulated that glutathione S-transferase functions physiologically as a hemin-binding and/or transport protein in developing erythroid cells.

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