Effect of Inhibition of Fatty Acid Oxidation on Neonatal Liver Carnitine Content

Overview

Journal Biochem J

Specialty Biochemistry

Date 1982 Jun 15

PMID 7126171

Authors

S C Frost

M A Wells

Affiliations

Soon will be listed here.

Abstract

The hypoglycaemic agent 2-tetradecylglycidic acid (compound McN-3802) caused an increase in total liver carnitine content, this being due primarily to an increase in the free carnitine pool. In the neonatal animal, this may represent a mechanism to overcome the inhibitory effect of fatty acid oxidation by the drug.

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