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Pharmacokinetic Comparison of Pindolol 30 Mg Retard and 15 Mg Normal Tablets

Overview
Journal Eur J Clin Pharmacol
Specialty Pharmacology
Date 1982 Jan 1
PMID 7075650
Citations 2
Authors
W H Aellig
E Nuesch
W Pacha
Affiliations
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Abstract

In a cross-over pharmacokinetic study in 8 healthy volunteers a retard formulation containing pindolol 30 mg was compared with the normal 15 mg. pindolol tablet. The pindolol 30 mg retard tablet led to the same maximum plasma level as a single dose of the normal pindolol tablet. A plasma concentration higher than half of the maximum was maintained twice as long after the retard than after the normal 15 mg pindolol tablet. The bioavailability of the two forms was practically identical.

Citing Articles

A pharmacodynamic and pharmacokinetic comparison of pindolol 20 mg retard and a conventional tablet.

Aellig W, Narjes H, Nuesch E, Oertle R, Devos J, Pacha W Eur J Clin Pharmacol. 1981; 20(3):179-83.

PMID: 7286035 DOI: 10.1007/BF00544595.

Simplified antihypertensive therapy with pindolol retard.

Kiowski W, Stumpe K, Buhler F Eur J Clin Pharmacol. 1982; 21(6):445-9.

PMID: 7075649 DOI: 10.1007/BF00542036.

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