» Articles » PMID: 7066180

The Role of the Meniscus in an Instability Model for Osteoarthritis in the Rabbit Knee

Overview
Journal Br J Exp Pathol
Specialty Pathology
Date 1982 Feb 1
PMID 7066180
Citations 4
Authors
Affiliations
Soon will be listed here.
Abstract

After division of the cruciate ligaments and one meniscus in the knee joint of the rabbit, degenerative changes were observed in both the articular cartilage and bone. This was more apparent on the tibial plateau in which the meniscus had been removed, progressive changes occurring from 3 to 16 weeks after trauma. A parallel in vitro experiment, involving measuring the lateral displacement of the tibia in the rabbit knee during medial-lateral leading, was performed before and after transverse division of the meniscus alone. The resulting displacements during medial-lateral shear loading approximately doubled after meniscectomy in the mechanical tests, the apparent clinical stability still being provided after meniscus division by the collateral ligaments, joint capsule, cruciates and bone geometry.

Citing Articles

Abnormal expression of key genes and proteins in the canonical Wnt/β-catenin pathway of articular cartilage in a rat model of exercise-induced osteoarthritis.

Liu S, Zhou P, Zhang Y Mol Med Rep. 2016; 13(3):1999-2006.

PMID: 26794964 PMC: 4768959. DOI: 10.3892/mmr.2016.4798.


The suppressive effect of hyaluronan on nitric oxide production and cell apoptosis in the central region of meniscus following partial meniscectomy.

Kobayashi K, Mishima H, Harwood F, Hashimoto S, Toyoguchi T, Goomer R Iowa Orthop J. 2002; 22:39-41.

PMID: 12180609 PMC: 1888363.


Factors affecting the prognosis of meniscectomy in soccer players.

Muckle D Br J Sports Med. 1983; 17(2):88-90.

PMID: 6688369 PMC: 1859010. DOI: 10.1136/bjsm.17.2.88.


Collagen orientations in the meniscus of the knee joint.

Aspden R, Yarker Y, Hukins D J Anat. 1985; 140 ( Pt 3):371-80.

PMID: 4066476 PMC: 1165103.

References
1.
Bullough P, Munuera L, Murphy J, Weinstein A . The strength of the menisci of the knee as it relates to their fine structure. J Bone Joint Surg Br. 1970; 52(3):564-7. View

2.
Hulth A, Lindberg L, TELHAG H . Experimental osteoarthritis in rabbits. Preliminary report. Acta Orthop Scand. 1970; 41(5):522-30. DOI: 10.3109/17453677008991540. View

3.
Walker P, Erkman M . The role of the menisci in force transmission across the knee. Clin Orthop Relat Res. 1975; (109):184-92. DOI: 10.1097/00003086-197506000-00027. View

4.
Maquet P, Van de Berg A, Simonet J . Femorotibial weight-bearing areas. Experimental determination. J Bone Joint Surg Am. 1975; 57(6):766-71. View

5.
Krause W, Pope M, Johnson R, Wilder D . Mechanical changes in the knee after meniscectomy. J Bone Joint Surg Am. 1976; 58(5):599-604. View