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Acute Anterior Uveitis and Klebsiella Aerogenes: a Casual Relationship?

Overview
Journal Br J Ophthalmol
Specialty Ophthalmology
Date 1981 Nov 1
PMID 7034772
Citations 4
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Abstract

This study was undertaken to investigate the hypothesis that episodes of anterior uveitis in patients with the HLA B27 antigen are triggered by the presence of Klebsiella aerogenes in the gastrointestinal tract. Forty patients were examined. While the recovery of klebsiella was greater in B27 positive patients with uveitis, the differences failed to reach statistical significance. The clinical state of patients with Klebsiella aerogenes in their faeces did not differ from that in whom klebsiella could not be recovered.

Citing Articles

A search for gram-negative enteric micro-organisms in acute anterior uveitis: association of klebsiella with recent onset of disease, HLA-B27, and B7 CREG.

White L, McCoy R, Tait B, Ebringer R Br J Ophthalmol. 1984; 68(10):750-5.

PMID: 6332644 PMC: 1040459. DOI: 10.1136/bjo.68.10.750.


IgG and IgA immune response against klebsiella in HLA-B27-associated anterior uveitis.

Kijlstra A, Luyendijk L, van der Gaag R, van Kregten E, Linssen A, Willers J Br J Ophthalmol. 1986; 70(2):85-8.

PMID: 3511961 PMC: 1040925. DOI: 10.1136/bjo.70.2.85.


Chlamydial antibody crossreactivity with peripheral blood mononuclear cells of patients with ankylosing spondylitis: the role of HLA B27.

Wakefield D, Easter J, Robinson P, Graham D, Penny R Clin Exp Immunol. 1986; 63(1):49-57.

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Acute anterior uveitis, arthritides and enteric antigens.

Szanto E, Granfors K, Wretlind B Clin Rheumatol. 1991; 10(4):395-400.

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References
1.
Nandi S . The histocompatability-2 locus and susceptibility to bittner virus borne by red blood cells in mice. Proc Natl Acad Sci U S A. 1967; 58(2):485-92. PMC: 335661. DOI: 10.1073/pnas.58.2.485. View

2.
Stokes P, Asquith P, Holmes G, Mackintosh P, COOKE W . Histocompatibility antigens associated with adult coeliac disease. Lancet. 1972; 2(7769):162-4. DOI: 10.1016/s0140-6736(72)91330-x. View

3.
BREWERTON D, Hart F, Nicholls A, Caffrey M, James D, Sturrock R . Ankylosing spondylitis and HL-A 27. Lancet. 1973; 1(7809):904-7. DOI: 10.1016/s0140-6736(73)91360-3. View

4.
McDevitt H, Bodmer W . HL-A, immune-response genes, and disease. Lancet. 1974; 1(7869):1269-75. DOI: 10.1016/s0140-6736(74)90021-x. View

5.
Edmonds J, Morris R, Metzger A, Bluestone R, Terasaki P, Ansell B . Follow-up study of juvenile chronic polyarthritis with particular reference to histocompatibility antigen W. 27. Ann Rheum Dis. 1974; 33(4):289-92. PMC: 1006259. DOI: 10.1136/ard.33.4.289. View