Genital Herpes Simplex

Overview

Journal Can Med Assoc J

Specialty General Medicine

Date 1981 Jul 1

PMID 7020907

Citations 5

Authors

I S Tummon

D K Dudley

J H Walters

Affiliations

Soon will be listed here.

Abstract

Genital herpes is a sexually transmitted disease caused by the herpes simplex virus. Following the initial infection the virus becomes latent in the sacral ganglia. Approximately 80% of patients are then subject to milder but unpredictable recurrences and may shed the virus even when they are asymptomatic. The disorder causes concern because genital herpes in the mother can result in rare but catastrophic neonatal infection and because of a possible association between genital herpes and cancer of the cervix. No effective treatment is as yet available. Weekly monitoring for virus by cervical culture from 32 weeks' gestation is recommended for women with a history of genital herpes and for those whose sexual partner has such a history.

Citing Articles

Impact of actin polymerization and filopodia formation on herpes simplex virus entry in epithelial, neuronal, and T lymphocyte cells.

Sasivimolrattana T, Bhattarakosol P Front Cell Infect Microbiol. 2023; 13:1301859.

PMID: 38076455 PMC: 10704452. DOI: 10.3389/fcimb.2023.1301859.

Neonatal herpes simplex.

Hammond G Can Med Assoc J. 1982; 126(5):468-9.

PMID: 6279266 PMC: 1863011.

Rapid detection and identification of herpes simplex virus in cell culture by a direct immunoperoxidase staining procedure.

Miller M, HOWELL C J Clin Microbiol. 1983; 18(3):550-3.

PMID: 6195177 PMC: 270852. DOI: 10.1128/jcm.18.3.550-553.1983.

Topical delivery of liposomally encapsulated interferon evaluated in a cutaneous herpes guinea pig model.

WEINER N, Williams N, Birch G, Ramachandran C, Shipman Jr C, Flynn G Antimicrob Agents Chemother. 1989; 33(8):1217-21.

PMID: 2802550 PMC: 172628. DOI: 10.1128/AAC.33.8.1217.

Comparison of the Scott Selecticult-HSV kit with conventional culture and direct immunoperoxidase staining for detection of herpes simplex virus in cultures of clinical specimens.

Johnson F, Leavitt R, Richards D J Clin Microbiol. 1985; 21(3):438-41.

PMID: 2579972 PMC: 271680. DOI: 10.1128/jcm.21.3.438-441.1985.

References

DeTure F, DRYLIE D, Kaufman H, Centifanto Y . Herpesvirus type2: study of semen in male subjects with recurrent infections. J Urol. 1978; 120(4):449-51. DOI: 10.1016/s0022-5347(17)57225-0. View

Curry J, Embil J, Williams C, Manuel F . Proctitis associated with Herpesvirus hominis type 2 infection. Can Med Assoc J. 1978; 119(5):485-6. PMC: 1818495. View

Fahim M, Brawner T, Millikan L, Nickell M, Hall D . New treatment for herpes simplex virus type 2 [ultrasound and zinc, urea, and tannic acid ointment]. Part I--Male patients. J Med. 1978; 9(3):245-64. View

Schneider G . Sexually transmissible vaginal infections in pregnancy. 2. Less common infections. Postgrad Med. 1979; 65(4):185-8. DOI: 10.1080/00325481.1979.11715122. View

Tobin S, Fish E, Cooter N, Papsin F . Relation of HVH-II to carcinoma of the cervix. Obstet Gynecol. 1979; 53(5):553-8. View

Amstey M, Monif G, Nahmias A, Josey W . Cesarean section and genital herpesvirus infection. Obstet Gynecol. 1979; 53(5):641-2. View

Sabin A . Are the herpes simplex-genitalis viruses a cause of certain human cancers?. Adv Pathobiol. 1976; (5):136-50. View

Nahmias A, Kawana T, Del Buono I . Clinicoepidemiologic aspects and association of genital herpes and cervical neoplasia. Adv Pathobiol. 1976; (5):42-53. View

Vontver L, REEVES W, Rattray M, Corey L, Remington M, Tolentino E . Clinical course and diagnosis of genital herpes simplex virus infection and evaluation of topical surfactant therapy. Am J Obstet Gynecol. 1979; 133(5):548-54. DOI: 10.1016/0002-9378(79)90290-4. View

10.

BLOUGH H, Giuntoli R . Successful treatment of human genital herpes infections with 2-deoxy-D-glucose. JAMA. 1979; 241(26):2798-2801. View

11.

Pazin G, Armstrong J, Lam M, Tarr G, Jannetta P, Ho M . Prevention of reactivated herpes simplex infection by human leukocyte interferon after operation on the trigeminal root. N Engl J Med. 1979; 301(5):225-30. DOI: 10.1056/NEJM197908023010501. View

12.

Miller J . Treatment of active herpes virus infections with influenza virus vaccine. Ann Allergy. 1979; 42(5):295-305. View

13.

Adam E, Kaufman R, Mirkovic R, Melnick J . Persistence of virus shedding in asymptomatic women after recovery from herpes genitalis. Obstet Gynecol. 1979; 54(2):171-3. View

14.

Andiman W . Congenital herpesvirus infections. Clin Perinatol. 1979; 6(2):331-46. View

15.

Parvey L, Chien L . Neonatal herpes simplex virus infection introduced by fetal-monitor scalp electrodes. Pediatrics. 1980; 65(6):1150-3. View

16.

Schnipper L, Crumpacker C . Resistance of herpes simplex virus to acycloguanosine: role of viral thymidine kinase and DNA polymerase loci. Proc Natl Acad Sci U S A. 1980; 77(4):2270-3. PMC: 348695. DOI: 10.1073/pnas.77.4.2270. View

17.

Whitley R, Nahmias A, Visintine A, Fleming C, Alford C . The natural history of herpes simplex virus infection of mother and newborn. Pediatrics. 1980; 66(4):489-94. View

18.

Guinan M, MacCalman J, Kern E, Overall Jr J, Spruance S . The course of untreated recurrent genital herpes simplex infection in 27 women. N Engl J Med. 1981; 304(13):759-63. DOI: 10.1056/NEJM198103263041305. View

19.

BESWICK T . The origin and the use of the word herpes. Med Hist. 1962; 6:214-32. PMC: 1034725. DOI: 10.1017/s002572730002737x. View

20.

Yen S, REAGAN J, Rosenthal M . HERPES SIMPLEX INFECTION IN FEMALE GENITAL TRACT. Obstet Gynecol. 1965; 25:479-92. View