A Double Blind Trial of Extra-amniotic Oestriol and Prostaglandin F2 Alpha Gels in Cervical Ripening

Overview

Journal Br J Obstet Gynaecol

Specialty Gynecology & Obstetrics

Date 1981 Jun 1

PMID 7018557

Citations 3

Authors

M A Quinn

A J Murphy

R J Kuhn

H P ROBINSON

J B Brown

Affiliations

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Abstract

Forty nulliparous patients with Bishop score of 3 or less were given 15 mg oestriol gel, 10 mg PGF2 alpha gel or gel alone via the extra-amniotic route. Both the oestriol and prostaglandin treated patients had a significant increase in Bishop score and a significant reduction in induction-delivery interval compared to controls. Oestriol gel had significantly less stimulatory effect on uterine activity than prostaglandin gel, indicating a possible local action.

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Dasgupta E, Singh G J Obstet Gynaecol India. 2013; 62(1):47-51.

PMID: 23372290 PMC: 3366577. DOI: 10.1007/s13224-012-0156-6.

Oestrogens alone or with amniotomy for cervical ripening or induction of labour.

Thomas J, Kelly A, Kavanagh J Cochrane Database Syst Rev. 2001; (4):CD003393.

PMID: 11687200 PMC: 6991160. DOI: 10.1002/14651858.CD003393.

Extra-amniotic prostaglandin for induction of labour.

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