» Articles » PMID: 7016924

Observations on 10 Years' HBs Antigenaemia After Renal Transplantation

Overview
Journal J Clin Pathol
Specialty Pathology
Date 1981 Apr 1
PMID 7016924
Authors
Affiliations
Soon will be listed here.
Abstract

A renal transplant patient became a carrier of HBs Ag within four weeks of a successful transplant. The level of antigenaemia was extremely high, and approximately 3% of the particles were 42 nm Dane particles, although the anti-HBe was present from at least 20 months after transplant. After four years the antigenaemia declined to a low level, and five years later HBs Ag became undetectable for the first time. During the past 18 months, no antigen has been detected although immunosuppression continues and the original kidney is still functional.

References
1.
Katchaki J, Siem T, Brouwer R . Serological evidence of presence of HBsAg undetectable by conventional radioimmunoassay in anti-HBc positive blood donors. J Clin Pathol. 1978; 31(9):837-9. PMC: 1145425. DOI: 10.1136/jcp.31.9.837. View

2.
NAGINGTON J . Chronic carriage of Australia antigen without symptoms after renal transplant. Br Med J. 1970; 4(5732):409-10. PMC: 1819949. DOI: 10.1136/bmj.4.5732.409. View

3.
Hoofnagle J, Gerety R, Barker L . Antibody to hepatitis-B-virus core in man. Lancet. 1973; 2(7834):869-73. DOI: 10.1016/s0140-6736(73)92004-7. View

4.
Kojima M, Udo K, Takahashi Y, Yoshizawa H, Tsuda F, Itoh Y . Correlation between titer of antibody to hepatitis B core antigen and presence of viral antigens in the liver. Gastroenterology. 1977; 73(4 Pt 1):664-7. View

5.
Vandervelde E, Mahmood N, Goffin C, Porter A, Megson B, Cossart Y . User's guide to some new tests for hepatitis-B antigen. Lancet. 1974; 2(7888):1066-8. DOI: 10.1016/s0140-6736(74)92164-3. View