Altered Regulation of the RecA Gene in Escherichia Coli Strains Carrying a RecA-linked Suppressor of LexA

Overview

Journal Mol Gen Genet

Specialties Genetics
Molecular Biology

Date 1980 Jan 1

PMID 7007810

Citations 9

Authors

A Thomas

R G Lloyd

Affiliations

Soon will be listed here.

Abstract

A mutant strain of E. coli displaying altered regulation of the recA gene was isolated as a revertant of a lexA3 recA200 double mutant which showed improved DNA repair and recombination functions. The mutant (alc-24) was located between srl and recA200 and caused synthesis of high levels of recA protein in both lexA+ and lexA3 strains. The possibility that alc-24 defines the regulatory site for recA is discussed.

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Nucleotide sequence of a recA operator mutation. LexA/operator-repressor binding/inducible repair.

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A molecular model for conjugational recombination in Escherichia coli K12.

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