Renal Transplantation in Children Less Than 5 Years of Age

Overview

Journal Arch Dis Child

Specialty Pediatrics

Date 1980 Jul 1

PMID 7002060

Citations 10

Authors

G Rizzoni

M H Malekzadeh

A J Pennisi

R B Ettenger

C H Uittenbogaart

R N Fine

Affiliations

Soon will be listed here.

Abstract

19 young children (less than 5 years old) have received 31 renal transplants from 4 live relatives and 27 cadaver donors. The 2-year allograft survival rate for the patients receiving their 1st allograft from the 4 live donors was 75 +/- 22% while for the patients receiving their 1st allograft from 15 cadaver donors was 26 +/- 11%. 10 children are currently surviving with functioning allographs (7 cadavers and 3 live relatives); 4 have died and 5 are undergoing dialysis after the loss of at least one allograft. Despite the poor allograft survival rate the fact that 7 children are surviving with cadaver allografts indicates that the lack of a living related donor should not prevent transplants in young children.

Citing Articles

The evolving ethics of infant dialysis.

Lantos J, Warady B Pediatr Nephrol. 2012; 28(10):1943-7.

PMID: 23131864 PMC: 3626731. DOI: 10.1007/s00467-012-2351-1.

Outcome of reaching end stage renal failure in children under 2 years of age.

Coulthard M, Crosier J Arch Dis Child. 2002; 87(6):511-7.

PMID: 12456551 PMC: 1755807. DOI: 10.1136/adc.87.6.511.

Comparison of high-dose intravenous methylprednisolone with low-dose oral prednisolone in acute renal allograft rejection in children.

Chantler C, Bewick M, Haycock G Br Med J (Clin Res Ed). 1982; 285(6337):258-60.

PMID: 6807439 PMC: 1499605. DOI: 10.1136/bmj.285.6337.258.

The outcome of 304 primary renal transplants in children (1968-1985).

Najarian J, So S, Simmons R, Fryd D, Nevins T, Ascher N Ann Surg. 1986; 204(3):246-58.

PMID: 3530152 PMC: 1251272. DOI: 10.1097/00000658-198609000-00004.

Transplantation in infants less than 1 year of age.

Nevins T Pediatr Nephrol. 1987; 1(2):154-6.

PMID: 3153273 DOI: 10.1007/BF00849287.

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