Endothelial-monocyte Antigens

Overview

Journal Transplant Proc

Specialty General Surgery

Date 1980 Sep 1

PMID 7001701

Citations 3

Authors

P Stastny

Affiliations

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Abstract

Monocyte cytotoxicity was found to be very dependent on selection of rabbit complement. Eluates obtained from kidney allografts were found to contain a variety of antibodies against monocytes, B cells, and T cells. Specific monocyte reactions were not blocked by an antiserum against human DR antigens made in chickens. A turkey serum against beta 2-microglobulin did abolish monocyte-specific reactions. Blocking with chicken anti-DR was used to assess antibodies in 56 alloantisera. Among the reactions observed, 52% were blocked by the anti-DR serum; 25% appeared to be monocyte-specific.

Citing Articles

Alloantigens expressed on a subset of unstimulated human T lymphocytes that generate suppressor function.

Okada J, Stastny P Immunogenetics. 1982; 16(1):59-70.

PMID: 6180983 DOI: 10.1007/BF00364442.

Inhibition of vessel allograft rejection by endothelial removal. Morphologic and ultrastructural changes.

Galumbeck M, Sanfilippo F, HAGEN P, Seaber A, Urbaniak J Ann Surg. 1987; 206(6):757-64.

PMID: 3500679 PMC: 1493339. DOI: 10.1097/00000658-198712000-00012.

MB1, a quail leukocyte-endothelium antigen: partial characterization of the cell surface and secreted forms in cultured endothelial cells.

Labastie M, Poole T, Peault B, Le Douarin N Proc Natl Acad Sci U S A. 1986; 83(23):9016-20.

PMID: 3466174 PMC: 387065. DOI: 10.1073/pnas.83.23.9016.