Antihypertensive Pharmacology
Overview
Authors
Affiliations
Although drug treatment of hypertension is associated with improved survival and decreased vascular complications, drug compliance is a major problem in the control of hypertension. All antihypertensive medications are associated with side effects; thus, it is a physician's responsibility to explain to each patient the side effects of the drugs he prescribes to treat hypertension, and to instill in the patient a sense of necessity for the treatment of hypertension. The choice of antihypertensive drug should be made based on each patient's lifestyle, overall health and ability to tolerate the drug. Ideally, the antihypertensive regimen should be simple, effective, convenient to take and have very few side effects.
Aziz M, Mohamed K, Farag D, Khalifa A, Mahmoud Z Sci Rep. 2024; 14(1):29514.
PMID: 39604410 PMC: 11603188. DOI: 10.1038/s41598-024-79697-1.
Bays H, Fitch A, Christensen S, Burridge K, Tondt J Obes Pillars. 2023; 2:100018.
PMID: 37990711 PMC: 10662004. DOI: 10.1016/j.obpill.2022.100018.
Nakade Y, Kitano R, Yamauchi T, Kimoto S, Sakamoto K, Inoue T Int J Mol Sci. 2021; 22(8).
PMID: 33920431 PMC: 8069855. DOI: 10.3390/ijms22083940.
Ghosh R, Bank S, Maji U, Bhattacharya R, Guha S, Khan N Int J Biomed Sci. 2014; 10(3):158-66.
PMID: 25324696 PMC: 4199471.
Hydralazine modifies Aβ fibril formation and prevents modification by lipids in vitro.
Maheshwari M, Roberts J, Desutter B, Duong K, Tingling J, Fawver J Biochemistry. 2010; 49(49):10371-80.
PMID: 21058733 PMC: 3033120. DOI: 10.1021/bi101249p.