Isotope Cisternography and Conductance to Outflow of CSF in Normal Pressure Hydrocephalus

Overview

Journal Acta Neurochir (Wien)

Specialty Neurosurgery

Date 1981 Jan 1

PMID 6973916

Citations 5

Authors

S E Borgesen

L Westergard

F Gjerris

Affiliations

Soon will be listed here.

Abstract

In 50 patients with normal pressure hydrocephalus (NPH) the findings on lumbar isotope cisternography (IGG) were compared to the conductance to outflow of CSF (Cout) as measured by lumbo-ventricular perfusion. The purpose was to identify those ICG-characteristics that imply a low Cout and thus may indicate CSF shunting therapy. Normal ICG was found only in three patients, where Cout was not, or only moderately, decreased. There was a significant correlation between a low Cout and occurrence of ventricular retention and absent parasagittal accumulation at 24 hours or later, following injection. These findings may, however, also be present in patients with no, or only moderate, decreased Cout, where CSF shunting may seen unjustified. It is concluded, that the indication for CSF shunting cannot be based on the results of ICG alone.

Citing Articles

The Effect of Body Posture on Brain Glymphatic Transport.

Lee H, Xie L, Yu M, Kang H, Feng T, Deane R J Neurosci. 2015; 35(31):11034-44.

PMID: 26245965 PMC: 4524974. DOI: 10.1523/JNEUROSCI.1625-15.2015.

Chronic hydrocephalus in adults.

Edwards R, Dombrowski S, Luciano M, Pople I Brain Pathol. 2004; 14(3):325-36.

PMID: 15446589 PMC: 8096062. DOI: 10.1111/j.1750-3639.2004.tb00072.x.

Conductance to outflow of CSF in normal pressure hydrocephalus.

Borgesen S Acta Neurochir (Wien). 1984; 71(1-2):1-45.

PMID: 6731051 DOI: 10.1007/BF01401149.

Resistance to cerebrospinal fluid outflow and intracranial pressure in patients with hydrocephalus after subarachnoid haemorrhage.

Gjerris F, Borgesen S, Sorensen P, Boesen F, Schmidt K, HARMSEN A Acta Neurochir (Wien). 1987; 88(3-4):79-86.

PMID: 3687503 DOI: 10.1007/BF01404142.

ICP dependent changes of CSF outflow resistance.

Tychmanowicz K, Czernicki Z, Pawlowski G, Stepinska G Acta Neurochir (Wien). 1992; 117(1-2):44-7.

PMID: 1514427 DOI: 10.1007/BF01400634.

References

Borgesen S, Gyldensted C, Gjerris F, Lester J . Computed tomography and pneumoencephalography compared to conductance to outflow of CSF in normal pressure hydrocephalus. Neuroradiology. 1980; 20(1):17-22. DOI: 10.1007/BF00346856. View

Hughes C, Siegel B, COXE W, Gado M, Grubb R, Coleman R . Adult idiopathic communicating hydrocephalus with and without shunting. J Neurol Neurosurg Psychiatry. 1978; 41(11):961-71. PMC: 493207. DOI: 10.1136/jnnp.41.11.961. View

Benson D, Lemay M, PATTEN D, Rubens A . Diagnosis of normal-pressure hydrocephalus. N Engl J Med. 1970; 283(12):609-15. DOI: 10.1056/NEJM197009172831201. View

Heinz E, DAVIS D, KARP H . Abnormal isotope cisternography in sympatomatic occult hydrocephalus. A correlative isotopic-neuroradiological study in 130 subjects. Radiology. 1970; 95(1):109-20. DOI: 10.1148/95.1.109. View

Wolinsky J, Barnes B, Margolis M . Diagnostic tests in normal pressure hydrocephalus. Neurology. 1973; 23(7):706-13. DOI: 10.1212/wnl.23.7.706. View

Coblentz J, Mattis S, ZINGESSER L, Kasoff S, Wisniewski H, Katzman R . Presenile dementia. Clinical aspects and evaluation of cerebrospinal fluid dynamics. Arch Neurol. 1973; 29(5):299-308. DOI: 10.1001/archneur.1973.00490290039003. View

SHENKIN H, Greenberg J, BOUZARTH W, Gutterman P, MORALES J . Ventricular shunting for relief of senile symptoms. JAMA. 1973; 225(12):1486-9. View

UDVARHELYI G, WOOD J, JAMES Jr A, Bartelt D . Results and complications in 55 shunted patients with normal pressure hydrocephalus. Surg Neurol. 1975; 3(5):271-5. View

Borgesen S, Gjerris F, SORENSEN S . Intracranial pressure and conductance to outflow of cerebrospinal fluid in normal-pressure hydrocephalus. J Neurosurg. 1979; 50(4):489-93. DOI: 10.3171/jns.1979.50.4.0489. View

10.

Illingworth R, Logue V, Symon L, Uemura K . The ventriculocaval shunt in the treatment of adult hydrocephalus. Results and complications in 101 patients. J Neurosurg. 1971; 35(6):681-5. DOI: 10.3171/jns.1971.35.6.0681. View

11.

JAMES Jr A, DeLand F, HODGES 3rd F, Wagner Jr H . Normal-pressure hydrocephalus. Role of cisternography in diagnosis. JAMA. 1970; 213(10):1615-22. DOI: 10.1001/jama.213.10.1615. View

12.

Symon L, Hinzpeter T . The enigma of normal pressure hydrocephalus: tests to select patients for surgery and to predict shunt function. Clin Neurosurg. 1977; 24:285-315. DOI: 10.1093/neurosurgery/24.cn_suppl_1.285. View

13.

Greenberg J, SHENKIN H, Adam R . Idiopathic normal pressure hydrocephalus-- a report of 73 patients. J Neurol Neurosurg Psychiatry. 1977; 40(4):336-41. PMC: 492700. DOI: 10.1136/jnnp.40.4.336. View

14.

DICHIRO G . NEW RADIOGRAPHIC AND ISOTOPIC PROCEDURES IN NEUROLOGICAL DIAGNOSIS. JAMA. 1964; 188:524-9. View

15.

Jacobs L, Conti D, KINKEL W, Manning E . "Normal-pressure" hydrocephalus. Relationship of clinical and radiographic findings to improvement following shunt surgery. JAMA. 1976; 235(5):510-2. DOI: 10.1001/jama.235.5.510. View

16.

Stein S, Langfitt T . Normal-pressure hydrocephalus. Predicting the results of cerebrospinal fluid shunting. J Neurosurg. 1974; 41(4):463-70. DOI: 10.3171/jns.1974.41.4.0463. View

17.

Borgesen S, Gjerris F, Srensen S . The resistance to cerebrospinal fluid absorption in humans. A method of evaluation by lumbo-ventricular perfusion, with particular reference to normal pressure hydrocephalus. Acta Neurol Scand. 1978; 57(1):88-96. DOI: 10.1111/j.1600-0404.1978.tb04500.x. View