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The Liquefaction (oncolysis) of Malignant Gliomas by a Non Pathogenic Clostridium

Overview
Journal Acta Neurochir (Wien)
Specialty Neurosurgery
Date 1978 Jan 1
PMID 696441
Citations 29
Authors
F Heppner
J R Mose
Affiliations
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Abstract

Vascular glioblastomas become liquefied when contaminated with spores of the non-pathogenic Clostridium butyricum M 55. The spores are administered by intracarotid injection. The oncolysis is complete one week after injection. The glioblastoma is converted into a brain abscess which is then operated on appropriately. Forty nine patients have been treated in this manner. The rate of recurrence, however, remained uninfluenced.

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References
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