Experimental Cryosurgical Lesion of the Optic Nerve
Overview
Overview
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
Abstract
The right optic nerves of three cynomolgus monkeys were frozen under direct visualization after a modified Kröhnlein operation. Left optic nerves were subjected to an identical procedure without freezing. Postoperatively, visual evoked responses (VERs) could not be obtained by stimulating right eyes, while electroretinograms from both eyes and VERs obtained by stimulating left eyes were normal. Extensive lesions which were found in the right optic nerves of all animals were histologically similar to those obtained by freezing in the brain.
References
1.
Laqua H, MACHEMER R
. Repair and adhesion mechanisms of the cryotherapy lesion in experimental retinal detachment. Am J Ophthalmol. 1976; 81(6):833-46.
DOI: 10.1016/0002-9394(76)90368-8.
View
2.
Miyazaki Y, Ervin F, Siegfried J, Richardson E, MARK V
. LOCALIZED COOLING IN THE CENTRAL NERVOUS SYSTEM. II. HISTOPATHOLOGICAL RESULTS. Arch Neurol. 1963; 9:392-9.
DOI: 10.1001/archneur.1963.00460100080009.
View
3.
DeVoe R, Ripps H, Vaughan Jr H
. Cortical responses to stimulation of the human fovea. Vision Res. 1968; 8(2):135-47.
DOI: 10.1016/0042-6989(68)90002-3.
View
4.
MERYMAN H
. Mechanics of freezing in living cells and tissues. Science. 1956; 124(3221):515-21.
DOI: 10.1126/science.124.3221.515.
View
5.
KLATZO I, Piraux A, LASKOWSKI E
. The relationship between edema, blood-brain-barrier and tissue elements in a local brain injury. J Neuropathol Exp Neurol. 1958; 17(4):548-64.
DOI: 10.1097/00005072-195810000-00002.
View