Elevated Rate of 3H-uridine Incorporation in Regressing Rat Ventral Prostate

Overview

Journal Invest Urol

Specialty Urology

Date 1978 Jul 1

PMID 689833

Citations 4

Authors

T Stanisic

R Sadlowski

C Lee

J T Grayhack

Affiliations

Soon will be listed here.

Abstract

Ventral prostates from adult Sprague-Dawley rats were removed at intervals during the first 2 weeks postcastration. Incubation of tissue with 3H-uridine and 3H-leucine was performed to determine the incorporation rate of radioactivity into the RNA and protein fractions respectively. Prostatic wet weight and 3H-leucine incorporation rate into prostate protein diminished postcastration, whereas 3H-uridine incorporation rate remained relatively high. The data suggest that RNA synthesis is relatively active in comparison with other parameters during regression.

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