Toxicity of Two Toxins from the Florida Red Tide Marine Dinoflagellate, Ptychodiscus Brevis

Overview

Journal Toxicon

Specialty Toxicology

Date 1982 Jan 1

PMID 6896247

Citations 30

Authors

D G Baden

T J MENDE

Affiliations

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Abstract

The purification and crystallization of T17, a toxin from Ptychodiscus brevis, is reported. The toxicity of this compound and a second toxin known as T34 are compared by i.v., i.p. and oral administration in mice. Both toxins produce symptoms characteristic of muscarnic stimulants; hypersalivation, rhinorrhea and excessive urination and defecation being the most commonly observed. T17, which is orally toxic, is believed to be the agent responsible for Neurotoxic Shellfish Poisoning.

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