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Ivermectin, a New Broad-spectrum Antiparasitic Agent

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Journal J Med Chem
Specialty Chemistry
Date 1980 Oct 1
PMID 6893469
Citations 55
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Abstract

22,23-Dihydroavermectin B1, ivermectin, derived from avermectin B1 by selective hydrogenation using Wilkinson's homogenous catalyst [Ph3P)3RhCl], was shown to be a highly effective drug for the treatment of a wide variety of metazoan parasitic diseases in animals.

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