Bactericidal Activity of a Granule Extract from Human Polymorphonuclear Leukocytes Against Bacteroides Species

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 1983 Sep 1

PMID 6885166

Citations 3

Authors

H Pruul

B L Wetherall

P J McDonald

Affiliations

Soon will be listed here.

Abstract

The microbicidal activity of an acetate extract of human polymorphonuclear leukocyte granules was tested against Bacteroides fragilis, Bacteroides vulgatus, Bacteroides distasonis and Bacteroides thetaiotaomicron. All strains tested were killed by the extract, and there were no significant differences between the different Bacteroides species.

Citing Articles

Oxygen-independent killing of Bacteroides fragilis by granule extracts from human polymorphonuclear leukocytes.

Wetherall B, Pruul H, McDonald P Infect Immun. 1984; 43(3):1080-4.

PMID: 6698601 PMC: 264297. DOI: 10.1128/iai.43.3.1080-1084.1984.

Growth of group IV mycobacteria on medium containing various saturated and unsaturated fatty acids.

Saito H, Tomioka H, Yoneyama T Antimicrob Agents Chemother. 1984; 26(2):164-9.

PMID: 6486760 PMC: 284112. DOI: 10.1128/AAC.26.2.164.

Role of myeloperoxidase in the killing of Naegleria fowleri by lymphokine-altered human neutrophils.

Ferrante A, Hill N, Abell T, Pruul H Infect Immun. 1987; 55(5):1047-50.

PMID: 3032797 PMC: 260466. DOI: 10.1128/iai.55.5.1047-1050.1987.

References

Johnston R, Newman S . Chronic granulomatous disease. Pediatr Clin North Am. 1977; 24(2):365-76. DOI: 10.1016/s0031-3955(16)33424-1. View

Onderdonk A, Kasper D, Cisneros R, Bartlett J . The capsular polysaccharide of Bacteroides fragilis as a virulence factor: comparison of the pathogenic potential of encapsulated and unencapsulated strains. J Infect Dis. 1977; 136(1):82-9. DOI: 10.1093/infdis/136.1.82. View

Babb J, CUMMINS C . Encapsulation of Bacteroides species. Infect Immun. 1978; 19(3):1088-91. PMC: 422300. DOI: 10.1128/iai.19.3.1088-1091.1978. View

Mandell G . Bactericidal activity of aerobic and anaerobic polymorphonuclear neutrophils. Infect Immun. 1974; 9(2):337-41. PMC: 414806. DOI: 10.1128/iai.9.2.337-341.1974. View

Ingham H, Sisson P, Middleton R, Narang H, Codd A, Selkon J . Phagocytosis and killing of bacteria in aerobic and anaerobic conditions. J Med Microbiol. 1981; 14(4):391-9. DOI: 10.1099/00222615-14-4-391. View

Tagesson C, Stendahl O . Influence of the cell surface lipopolysaccharide structure of Salmonella typhimurium on resistance to intracellular bactericidal systems. Acta Pathol Microbiol Scand B Microbiol Immunol. 1973; 81(4):473-80. DOI: 10.1111/j.1699-0463.1973.tb02232.x. View

Kasper D, Onderdonk A, Reinap B, Linberg A . Variations of Bacteroides fragilis with in vitro passage: presence of an outer membrane-associated glycan and loss of capsular antigen. J Infect Dis. 1980; 142(5):750-6. DOI: 10.1093/infdis/142.5.750. View

Weiss J, Elsbach P . Resistance of gram-negative bacteria to purified bactericidal leukocyte proteins: relation to binding and bacterial lipopolysaccharide structure. J Clin Invest. 1980; 65(3):619-28. PMC: 371403. DOI: 10.1172/JCI109707. View

Simon G, Klempner M, Kasper D, Gorbach S . Alterations in opsonophagocytic killing by neutrophils of Bacteroides fragilis associated with animal and laboratory passage: effect of capsular polysaccharide. J Infect Dis. 1982; 145(1):72-7. DOI: 10.1093/infdis/145.1.72. View

10.

Selvaraj R, Sbarra A . Relationship of glycolytic and oxidative metabolism to particle entry and destruction in phagocytosing cells. Nature. 1966; 211(5055):1272-6. DOI: 10.1038/2111272a0. View

11.

Dechatelet L . Initiation of the respiratory burst in human polymorphonuclear neutrophils: a critical review. J Reticuloendothel Soc. 1978; 24(1):73-91. View

12.

Polk B, Kasper D . Bacteroides fragilis subspecies in clinical isolates. Ann Intern Med. 1977; 86(5):569-71. DOI: 10.7326/0003-4819-86-5-569. View

13.

Quie P . Bactericidal function of human polymorphonuclear leukocytes. E. Mead Johnson Award Address. Pediatrics. 1972; 50(2):264-70. View

14.

Okamura N, Spitznagel J . Outer membrane mutants of Salmonella typhimurium LT2 have lipopolysaccharide-dependent resistance to the bactericidal activity of anaerobic human neutrophils. Infect Immun. 1982; 36(3):1086-95. PMC: 551442. DOI: 10.1128/iai.36.3.1086-1095.1982. View

15.

Klebanoff S . Antimicrobial mechanisms in neutrophilic polymorphonuclear leukocytes. Semin Hematol. 1975; 12(2):117-42. View

16.

McRipley R, Sbarra A . Role of the phagocyte in host-parasite interactions. XI. Relationship between stimulated oxidative metabolism and hydrogen peroxide formation, and intracellular killing. J Bacteriol. 1967; 94(5):1417-24. PMC: 276841. DOI: 10.1128/jb.94.5.1417-1424.1967. View

17.

Rest R, Cooney M, Spitznagel J . Susceptibility of lipopolysaccharide mutants to the bactericidal action of human neutrophil lysosomal fractions. Infect Immun. 1977; 16(1):145-51. PMC: 421501. DOI: 10.1128/iai.16.1.145-151.1977. View

18.

Weiss J, Victor M, Stendhal O, Elsbach P . Killing of gram-negative bacteria by polymorphonuclear leukocytes: role of an O2-independent bactericidal system. J Clin Invest. 1982; 69(4):959-70. PMC: 370150. DOI: 10.1172/jci110535. View

19.

Kasper D, Hayes M, Reinap B, Craft F, Onderdonk A, Polk B . Isolation and identification of encapsulated strains of Bacteroides fragilis. J Infect Dis. 1977; 136(1):75-81. DOI: 10.1093/infdis/136.1.75. View

20.

Friedberg D, Shilo M . Interaction of Gram-Negative Bacteria with the Lysosomal Fraction of Polymorphonuclear Leukocytes I. Role of Cell Wall Composition of Salmonella typhimurium. Infect Immun. 1970; 1(3):305-10. PMC: 415897. DOI: 10.1128/iai.1.3.305-310.1970. View