A Possible Ca2+-induced Ca2+ Release Mechanism Mediated by Norepinephrine in Vascular Smooth Muscle
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In vascular smooth muscle, the norepinephrine-sensitive Ca2+ store is distinct from the sarcoplasmic reticulum. Under physiological conditions, Ca2+ released from the norepinephrine-sensitive store may induce Ca2+ release from the sarcoplasmic reticulum, i.e. norepinephrine mediated activation may involve a Ca2+-induced Ca2+ release mechanism.
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