Transovarial Transmission of Dengue 2 Virus by Aedes Aegypti in Nature

Overview

Journal Am J Trop Med Hyg

Specialty Tropical Medicine

Date 1983 May 1

PMID 6859404

Citations 30

Authors

M M Khin

K A Than

Affiliations

Soon will be listed here.

Abstract

Dengue 2 virus was recovered from three of 123 pools of naturally infected Aedes aegypti larvae (6,200 insects) collected from water containers in Rangoon. The virus was also isolated from two of 76 pools (7,730 mosquitoes) of male Ae. aegypti, collected as larvae and reared in the laboratory to adults. Minimum field infection rates among these two groups of mosquitoes were 1:2,067 and 1:3,865, respectively. Insect pools were inoculated into Toxorhynchites splendens mosquitoes and dengue viral antigen was subsequently detected in headsquash preparations by direct fluorescent antibody technique. Identification of the dengue serotype was done by complement-fixation test. This is the first report of dengue virus isolation from naturally infected mosquito larvae. These findings suggest that transovarial transmission of dengue virus occurs in nature.

Citing Articles

Development of an Enzyme-Linked Immunosorbent Assay (ELISA) as a tool to detect NS1 of dengue virus serotype 2 in female eggs for the surveillance of dengue fever transmission.

Argotte-Ramos R, Cime-Castillo J, Vargas V, Lanz-Mendoza H, Rodriguez M, Rodriguez M Heliyon. 2024; 10(8):e29329.

PMID: 38681627 PMC: 11053180. DOI: 10.1016/j.heliyon.2024.e29329.

Wolbachia wMel strain-mediated effects on dengue virus vertical transmission from Aedes aegypti to their offspring.

Duong Thi Hue K, Da Silva Goncalves D, Tran Thuy V, Thi Vo L, Le Thi D, Vu Tuyet N Parasit Vectors. 2023; 16(1):308.

PMID: 37653429 PMC: 10472731. DOI: 10.1186/s13071-023-05921-y.

Inhibition of 3-Hydroxykynurenine Transaminase from and : A Mosquito-Specific Target to Combat the Transmission of Arboviruses.

Maciel L, Ferraz M, Oliveira A, Lins R, Dos Anjos J, Guido R ACS Bio Med Chem Au. 2023; 3(2):211-222.

PMID: 37101811 PMC: 10125267. DOI: 10.1021/acsbiomedchemau.2c00080.

Aedes larval bionomics and implications for dengue control in the paradigmatic Jaffna peninsula, northern Sri Lanka.

Surendran S, Jayadas T, Thiruchenthooran V, Raveendran S, Tharsan A, Santhirasegaram S Parasit Vectors. 2021; 14(1):162.

PMID: 33736702 PMC: 7977581. DOI: 10.1186/s13071-021-04640-6.

Evidence of transovarial transmission of Chikungunya and Dengue viruses in field-caught mosquitoes in Kenya.

Heath C, Grossi-Soyster E, Ndenga B, Mutuku F, Sahoo M, Ngugi H PLoS Negl Trop Dis. 2020; 14(6):e0008362.

PMID: 32559197 PMC: 7329127. DOI: 10.1371/journal.pntd.0008362.