Cerebral Involvement in Dehydration-induced Natriuresis

Overview

Journal Brain Res

Specialty Neurology

Date 1983 Mar 21

PMID 6839180

Citations 5

Authors

M J McKinley

D A Denton

R G Park

R S Weisinger

Affiliations

Soon will be listed here.

Abstract

Water deprivation caused daily urinary Na output to more than double in normal sheep, but caused no increase in Na excretion in sheep (A3VL-sheep) in which the anterior third ventricle wall had been ablated. Dehydrated A3VL-sheep exhibited a much greater degree of hypernatremia than dehydrated normal sheep, although water losses were similar in both groups. We postulate that the natriuresis induced by dehydration is a cerebrally mediated homeostatic response.

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