A Histopathological and Histochemical Study of the Ovaries of Mice Experimentally Infected with Schistosoma Mansoni

Overview

Journal Br J Exp Pathol

Specialty Pathology

Date 1983 Feb 1

PMID 6838760

Authors

H Abaza

L Asser

S M Abdel Reheim

N Shaaban

S K Marei

M A Hagras

Affiliations

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Abstract

Thirty-two female mice infected with Schistosoma mansoni and 16 non-infected control mice were studied. They were killed by cervical dislocation, dissected and their ovaries examined histopathologically and histochemically. Ovaries of infected mice showed definite structural damage. No ova, worms or specific granulomata were detected. The study points to a possible immunological mechanism producing such changes simulating those occurring in schistosomal nephropathy. Detection of immune complexes in such organs is recommended.

References

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