Humoral Immune Response in Acquired Immunity to Chlamydial Genital Infection of Female Guinea Pigs

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 1983 Jan 1

PMID 6822430

Citations 45

Authors

R G Rank

A L Barron

Affiliations

Soon will be listed here.

Abstract

Immunity to reinfection in the genital tract of female guinea pigs with the agent of guinea pig inclusion conjunctivitis was found to be dependent upon an intact humoral immune response. Cell-mediated immunity in the absence of humoral immunity had no apparent role in resistance to challenge infection.

Citing Articles

Human genital antibody-mediated inhibition of Chlamydia trachomatis infection and evidence for ompA genotype-specific neutralization.

Ardizzone C, Albritton H, Lillis R, Bagnetto C, Shen L, Cavacini L PLoS One. 2021; 16(10):e0258759.

PMID: 34662351 PMC: 8523062. DOI: 10.1371/journal.pone.0258759.

Cross-Reactive Effects of Vaccines: Heterologous Immunity between Tetanus and Chlamydia.

Stojanovic M, Lukic I, Marinkovic E, Kovacevic A, Miljkovic R, Tobias J Vaccines (Basel). 2020; 8(4).

PMID: 33271962 PMC: 7712554. DOI: 10.3390/vaccines8040719.

L2c Infection in a Porcine Model Produced Urogenital Pathology and Failed to Induce Protective Immune Responses Against Re-Infection.

De Clercq E, Van Gils M, Schautteet K, Devriendt B, Kiekens C, Chiers K Front Immunol. 2020; 11:555305.

PMID: 33193323 PMC: 7649141. DOI: 10.3389/fimmu.2020.555305.

-Specific IgA Secretion in the Female Reproductive Tract Induced via Per-Oral Immunization Confers Protection against Primary Challenge.

Shillova N, Howe S, Hyseni B, Ridgell D, Fisher D, Konjufca V Infect Immun. 2020; 89(1).

PMID: 33139380 PMC: 7927933. DOI: 10.1128/IAI.00413-20.

A novel whole-bacterial enzyme linked-immunosorbant assay to quantify Chlamydia trachomatis specific antibodies reveals distinct differences between systemic and genital compartments.

Albritton H, Kozlowski P, Lillis R, McGowin C, Siren J, Taylor S PLoS One. 2017; 12(8):e0183101.

PMID: 28797112 PMC: 5552291. DOI: 10.1371/journal.pone.0183101.

References

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LAMONT H, Semine D, Leveille C, Nichols R . Immunity to vaginal reinfection in female guinea pigs infected sexually with Chlamydia of guinea pig inclusion conjunctivitis. Infect Immun. 1978; 19(3):807-13. PMC: 422260. DOI: 10.1128/iai.19.3.807-813.1978. View