Alpha 2.0

» Articles » PMID: 6803946

Gall-stone Dissolution and Recurrence: Are We Being Misled?

Overview

Overview

Journal Br Med J (Clin Res Ed)

Specialty General Medicine

Date 1982 May 1

PMID 6803946

Citations 9

Authors

Authors

K W Somerville

D H Rose

G D Bell

W R Ellis

D R Knapp

Affiliations

Affiliations

Soon will be listed here.

Abstract

Oral cholecystography repeated at six-months intervals is the standard method for determining reduction in size of gall stones (partial success) and complete dissolution of stones (complete success). In a comparative study of oral cholecystography and cholecystosonography six out of 14 patients with gall stones achieving complete success by oral cholecystographic criteria had stones still detectable by ultrasonography. Repeat oral cholecystography in a further 11 patients receiving post-dissolution maintenance treatment detected stones in two, whereas ultrasonography detected stones in seven. In future complete dissolution of gall stones should be reported only if both oral cholecystography and ultrasonographic studies give negative results and the progress of patients receiving post-dissolution maintenance treatment is monitored by ultrasonography rather than serial oral cholecystography.

Citing Articles

Gallbladder stone recurrence after medical treatment. Do gallstones recur true to type?.

Pereira S, Hussaini S, Kennedy C, Dowling R Dig Dis Sci. 1995; 40(12):2568-75.

PMID: 8536514 DOI: 10.1007/BF02220443.

Gall stone recurrence and its prevention: the British/Belgian Gall Stone Study Group's post-dissolution trial.

Hood K, Gleeson D, Ruppin D, Dowling R Gut. 1993; 34(9):1277-88.

PMID: 8406169 PMC: 1375471. DOI: 10.1136/gut.34.9.1277.

Management of stones in the biliary tree.

Dowling R Gut. 1983; 24(7):599-608.

PMID: 6862283 PMC: 1420031. DOI: 10.1136/gut.24.7.599.

Gall-stone dissolution and recurrence: are we being misled?.

Br Med J (Clin Res Ed). 1982; 285(6335):131-3.

PMID: 6805831 PMC: 1498895. DOI: 10.1136/bmj.285.6335.131-a.

Progress in gall stone disease.

Bateson M Br Med J (Clin Res Ed). 1984; 289(6453):1163-4.

PMID: 6437469 PMC: 1443309. DOI: 10.1136/bmj.289.6453.1163.

References

1.

Danzinger R, Hofmann A, SCHOENFIELD L, Thistle J . Dissolution of cholesterol gallstones by chenodeoxycholic acid. N Engl J Med. 1972; 286(1):1-8. DOI: 10.1056/NEJM197201062860101. View

2.

Bell G, Whitney B, Dowling R . Gallstone dissolution in man using chenodeoxycholic acid. Lancet. 1972; 2(7789):1213-6. DOI: 10.1016/s0140-6736(72)92266-0. View

3.

Thistle J, Hofmann A . Efficacy and specificity of chenodeoxycholic acid therapy for dissolving gallstones. N Engl J Med. 1973; 289(13):655-9. DOI: 10.1056/NEJM197309272891303. View

4.

Bell G . The present position concerning gallstone dissolution. Gut. 1974; 15(11):913-29. PMC: 1413052. DOI: 10.1136/gut.15.11.913. View

5.

Bartrum Jr R, Crow H, Foote S . Ultrasonic and radiographic cholecystography. N Engl J Med. 1977; 296(10):538-41. DOI: 10.1056/NEJM197703102961004. View

6.

Nakagawa S, Makino I, Ishizaki T, DOHI I . Dissolution of cholesterol gallstones by ursodeoxycholic acid. Lancet. 1977; 2(8034):367-9. DOI: 10.1016/s0140-6736(77)90301-4. View

7.

Anderson J, Harned R . Gray scale ultrasonography of the gallbladder: an evaluation of accuracy and report of additional ultrasound signs. AJR Am J Roentgenol. 1977; 129(6):975-7. DOI: 10.2214/ajr.129.6.975. View

8.

Bell G, Doran J . Gall stone dissolution in man using an essential oil preparation. Br Med J. 1979; 1(6155):24. PMC: 1597519. DOI: 10.1136/bmj.1.6155.24. View

9.

Cooperberg P, Pon M, Wong P, Stoller J, Burhenne H . Real-time high resolution ultrasound in the detection of biliary calculi. Radiology. 1979; 131(3):789-90. DOI: 10.1148/131.3.789. View

10.

Ellis W, Bell G, Middleton B, White D . Adjunct to bile-acid treatment for gall-stone dissolution: low-dose chenodeoxycholic acid combined with a terpene preparation. Br Med J (Clin Res Ed). 1981; 282(6264):611-2. PMC: 1504429. DOI: 10.1136/bmj.282.6264.611-a. View

11.

Simeone J, Ferrucci Jr J . New trends in gallbladder imaging. JAMA. 1981; 246(4):380-3. View

12.

Bateson M, Bouchier I, Trash D, Maudgal D, Northfield T . Calcification of radiolucent gall stone during treatment with ursodeoxycholic acid. Br Med J (Clin Res Ed). 1981; 283(6292):645-6. PMC: 1506766. DOI: 10.1136/bmj.283.6292.645. View

13.

SCHOENFIELD L, Lachin J . Chenodiol (chenodeoxycholic acid) for dissolution of gallstones: the National Cooperative Gallstone Study. A controlled trial of efficacy and safety. Ann Intern Med. 1981; 95(3):257-82. DOI: 10.7326/0003-4819-95-3-257. View

14.

POLLI E, Bianchi P, Conte D, Sironi L . Treatment of radiolucent gallstones with CDCA or UDCA. A multicenter trial. Digestion. 1981; 22(4):185-91. DOI: 10.1159/000198643. View

15.

Ruppin D, Dowling R . Is recurrence inevitable after gallstone dissolution by bile-acid treatment?. Lancet. 1982; 1(8265):181-5. DOI: 10.1016/s0140-6736(82)90757-7. View