Gonadotrophin Response to LH-RH in Boys with Delayed Growth and Adolescence

Overview

Journal Arch Dis Child

Specialty Pediatrics

Date 1981 Jul 1

PMID 6791593

Citations 4

Authors

M O Savage

M A Preece

N Cameron

J Jones

G Theintz

J L Penfold

J M Tanner

Affiliations

Soon will be listed here.

Abstract

Plasma luteinising hormone (LH) and follicle-stimulating hormone (FSH) concentrations were measured before and after intravenous luteinising hormone-releasing hormone (LH-RH) in 33 boys with growth delay. Eighteen were prepubertal and 15 pubertal. Basal LH and FSH levels were low in both groups with mean increments after LH-RH of 3.2 +/- 0.8 U/l (mean +/- SEM) and 2.6 +/- 0.4 U/l respectively in the prepubertal and 7.4 +/- 0.7 U/l and 2.0 +/- 0.3 U/l in the pubertal boys. The LH increment showed a positive correlation with increasing bone age (r = 0.71, P less than 0.001); FSH did not. The LH-RH response thus appeared normal in relation to the stage of maturity.

Citing Articles

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